ReviewNutrients2018
Dietary Magnesium and Cardiovascular Disease: A Review with Emphasis in Epidemiological Studies.
Review in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 3 syntheses or guidelines pooled it, 171 citations in OpenAlex.
- Comprehensive Effects of Magnesium Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Dose-Response Meta-Analysis.Nutrients · 2026Pooled it
- The effect of magnesium supplementation on serum concentration of lipid profile: an updated systematic review and dose-response meta-analysis on randomized controlled trials.Nutrition journal · 2025Pooled it
- Effectively Prescribing Oral Magnesium Therapy for Hypertension: A Categorized Systematic Review of 49 Clinical Trials.Nutrients · 2021Pooled it
- Magnesium sulphate in patients with thrombotic thrombocytopenic purpura (MAGMAT): a randomised, double-blind, superiority trial.Intensive care medicine · 2023Trial
- Association of serum essential and non-essential elements with dyslipidemia in patients with cardiovascular disease in Western Iran: an application of Bayesian kernel machine regression.BMC cardiovascular disorders · 2026Article
- Magnesium at the Neurovascular Interface: A Narrative Review of Atherosclerosis, Peripheral Arterial Disease, and Neuropathic Pain.Nutrients · 2026Review
- The Nutritional Paradox of Obesity: Mechanisms and Clinical Implications of Micronutrient Deficiencies.Medical sciences (Basel, Switzerland) · 2026Review
- Hypomagnesemia: A Clinical and Nutritional Update.Current nutrition reports · 2026Review
- Review
- Magnesium Oxide Use and Clinical Outcomes in CKD Patients: Evidence from a Nationwide Population-Based Cohort Study in Taiwan.International journal of medical sciences · 2026Article
- Micronutrients in relation to cardiometabolic risk factors among middle-aged and older Chinese adults: protocol for an exploratory longitudinal panel study with multi-omics profiling.Frontiers in public health · 2026Article
- Essential and Toxic Elements in Cardiovascular Disease: Pathophysiological Roles and the Emerging Contribution of Hair Mineral Analysis.International journal of molecular sciences · 2025Review
- Differences in Cardiovascular, Biochemical and Nutritional Parameters Between High- and Low-Altitude Winter Sports Athletes.Nutrients · 2025Article
- Cardiometabolic Biomarkers and Cardiovascular Risk Stratification in Polish Military Personnel: A Chemometric Approach.International journal of molecular sciences · 2025Article
- Dietary Calcium to Magnesium Ratio and Risk of Cardiovascular Diseases.Biological trace element research · 2025Article
- Magnesium Depletion Score as an Indicator of Health Risk and Nutritional Status-A Scoping Review.Nutrients · 2025Article
- The prognostic value of serum MgEndocrine · 2025Article
- Effect of serum magnesium level on carotid intima media thickness in hemodialysis patients.BMC nephrology · 2025Article
- Plant-based dietary indices association with appetite, appetite regulating peptides and gut microbiota in healthy women: a cross-sectional study.European journal of nutrition · 2025Article
- Magnesium-rich diet score is inversely associated with incident cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study.European journal of preventive cardiology · 2025Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Magnesium (Mg) is an essential dietary element for humans involved in key biological processes. A growing body of evidence from epidemiological studies, randomized controlled trials (RCTs) and meta-analyses have indicated inverse associations between Mg intake and cardiovascular diseases (CVD). The present review aims to summarize recent scientific evidence on the topic, with a focus on data from epidemiological studies assessing the associations between Mg intake and major cardiovascular (CV) risk factors and CVD. We also aimed to review current literature on circulating Mg and CVD, as well as potential biological processes underlying these observations. We concluded that high Mg intake is associated with lower risk of major CV risk factors (mainly metabolic syndrome, diabetes and hypertension), stroke and total CVD. Higher levels of circulating Mg are associated with lower risk of CVD, mainly ischemic heart disease and coronary heart disease. Further, RCTs and prospective studies would help to clarify whether Mg intake and Mg circulating levels may also protect against other CVDs and CVD death.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.