ArticleJournal of food and drug analysis2018
Metabolic profiling investigation of Fritillaria thunbergii Miq. by gas chromatography-mass spectrometry.
Article in Journal of food and drug analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 40 citations in OpenAlex.
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- Application of metabolomics in quality control of traditional Chinese medicines: a review.Frontiers in plant science · 2024Review
- Fast Detection of Heavy Metal Content inMolecules (Basel, Switzerland) · 2023Article
- Simultaneous Determination of 108 Pesticide Residues in Three Traditional Chinese Medicines Using a Modified QuEChERS Mixed Sample Preparation Method and HPLC-MS/MS.Molecules (Basel, Switzerland) · 2022Article
- UHPLC-Q-Exactive Orbitrap MS/MS-Based Untargeted Metabolomics and Molecular Networking Reveal the Differential Chemical Constituents of the Bulbs and Flowers ofMolecules (Basel, Switzerland) · 2022Article
- Plant Virome Analysis by the Deep Sequencing of Small RNAs of Fritillaria thunbergii var. chekiangensis and the Rapid Identification of Viruses.The plant pathology journal · 2022Article
- Real-time fluorescence and colorimetric identification of bulbus fritillariae using recombinase assisted loop-mediated isothermal DNA amplification (RALA).Frontiers in plant science · 2022Article
- Systematic Analysis Strategy Based on Network Pharmacology to Investigate the Potential Mechanism ofEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Efficacy, chemical composition, and pharmacological effects of herbal drugs derived fromFrontiers in pharmacology · 2022Article
- Plants Metabolome Study: Emerging Tools and Techniques.Plants (Basel, Switzerland) · 2021Review
- Natural drug sources for respiratory diseases from Fritillaria: chemical and biological analyses.Chinese medicine · 2021Review
- Network Pharmacology Analysis of the Therapeutic Mechanisms Underlying Beimu-Gualou Formula Activity against Bronchiectasis withEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Identification of the Molecular Mechanisms of Peimine in the Treatment of Cough Using Computational Target Fishing.Molecules (Basel, Switzerland) · 2020Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thunberg fritillary bulb (the dry bulbs of Fritillaria thunbergii Miq.), a traditional Chinese Medicine, is widely applied as an expectorant and antitussive. In this investigation, the primary metabolites of bulbs, flowers, leaves, and stems of F. thunbergii were analyzed by gas chromatography-mass spectrometry. Principal component analysis, partial least squares-discriminate analysis, orthogonal projection to latent structures-discriminate analysis, and heat map analysis showed that there were dissimilar metabolites, and a negative correlation between amino acids and saccharides in different analytes. Furthermore, carbodiimide, tryptophan, glucose-6-phosphate, xylose, 2-piperidinecarboxylic acid, monoamidomalonic acid, phenylalanine, and histidine were found to play an important role in the plant metabolism net of F. thunbergii.
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