Evidence map›Paper›PMID 29389551›Full record

ArticleJournal of food and drug analysis2018

Hypocholesterolemic activity of indigenous probiotic isolate Saccharomyces cerevisiae ARDMC1 in a rat model.

Devabrata Saikia, Ajay Kumar Manhar, Bhagyashree Deka, Raju Roy, Kuldeep Gupta, Nima D Namsa, Pronobesh Chattopadhyay, Robin Doley, Manabendra Mandal

Open access · hybridAbstract read
In one paragraph

Article in Journal of food and drug analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
  2. Characterizing probiotic properties of the Saccharomyces cerevisiae ABO1 strain isolated from toddy palm nectar.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  3. Article
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  7. Heliyon · 2023
    Article
  8. Investigating the Efficacy ofInternational journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Devabrata SaikiaDepartment of Molecular Biology and Biotechnology, Tezpur University, Tezpur-784028, Assam, India.
Ajay Kumar ManharDepartment of Molecular Biology and Biotechnology, Tezpur University, Tezpur-784028, Assam, India.
Bhagyashree DekaDepartment of Molecular Biology and Biotechnology, Tezpur University, Tezpur-784028, Assam, India.
Raju RoyDepartment of Molecular Biology and Biotechnology, Tezpur University, Tezpur-784028, Assam, India.
Kuldeep GuptaDepartment of Molecular Biology and Biotechnology, Tezpur University, Tezpur-784028, Assam, India.
Nima D NamsaDepartment of Molecular Biology and Biotechnology, Tezpur University, Tezpur-784028, Assam, India.
Pronobesh ChattopadhyayDivision of Pharmaceutical Technology, Defence Research Laboratory, Tezpur 784001, Assam, India.
Robin DoleyDepartment of Molecular Biology and Biotechnology, Tezpur University, Tezpur-784028, Assam, India.
Manabendra MandalDepartment of Molecular Biology and Biotechnology, Tezpur University, Tezpur-784028, Assam, India.
Tezpur University · INDefence Research Laboratory · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate probiotic attributes of Saccharomyces cerevisiae ARDMC1 isolated from traditional rice beer starter cake and its hypocholesterolemic effects on Wistar rats fed a high-cholesterol diet. The indigenous isolate ARDMC1 showed potential probiotic characteristics such as tolerance to simulated gastrointestinal stress conditions, autoaggregation properties, and adhesion to intestinal epithelium Caco-2 cell line. In addition, ARDMC1 isolate exhibited in vitro cholesterol assimilation properties in media supplemented with cholesterol. Furthermore, administration of probiotic isolate to rats fed a hypercholesterolemic diet resulted in significant reduction of serum total cholesterol, low-density lipoprotein cholesterol, and triglyceride at the end of 42 days. The present study envisages ARDMC1 as a promising starter culture for the preparation of functional foods with properties to combat cardiovascular diseases.

Indexed as

Anticholesteremic AgentsDietary SupplementsProbioticsSaccharomyces cerevisiaeAnimalsCell LineDisease Models, AnimalHumansHydrophobic and Hydrophilic InteractionsHypercholesterolemiaLipidsRatsStress, PhysiologicalAnticholesteremic AgentsLipidsatherogenic indexcholesterol loweringin vivo modelProbiotic yeast

Identifiers

PMID29389551
PMCPMC9332649
OpenAlexW2588905721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.