ArticleMedical physics2018
A dedicated breast-PET/CT scanner: Evaluation of basic performance characteristics.
Article in Medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Design and imaging performance of BPET-DBT - a dedicated scanner for breast imaging.Medical physics · 2026Article
- Experimental determination of PET modulation transfer functions incorporating positron range effects using an oversampled cylindrical source.Medical physics · 2026Article
- Multi-angle acquisition and 3D composite reconstruction for organ-targeted PET using planar detectors.Medical physics · 2025Article
- Construction and evaluation of a large radiation detector for Positron Emission Tomography applications.Journal of instrumentation : an IOP and SISSA journal · 2024Article
- Advances in Breast PET Instrumentation.PET clinics · 2024Review
- The quest for multifunctional and dedicated PET instrumentation with irregular geometries.Annals of nuclear medicine · 2024Review
- A dedicated breast-PET/CT scanner: Numerical observer study of lesion detection.Medical physics · 2022Article
- Dedicated breast CT: state of the art-Part II. Clinical application and future outlook.European radiology · 2022Review
- Dedicated breast CT: state of the art-Part I. Historical evolution and technical aspects.European radiology · 2022Review
- Application-specific nuclear medicalPhysics in medicine and biology · 2021Review
- Evaluating attenuation correction strategies in a dedicated, single-gantry breast PET-tomosynthesis scanner.Physics in medicine and biology · 2020Article
- Impact of Using Uniform Attenuation Coefficients for Heterogeneously Dense Breasts in a Dedicated Breast PET/X-ray Scanner.IEEE transactions on radiation and plasma medical sciences · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
purposeApplication of advanced imaging techniques, such as PET and x ray CT, can potentially improve detection of breast cancer. Unfortunately, both modalities have challenges in the detection of some lesions. The combination of the two techniques, however, could potentially lead to an overall improvement in diagnostic breast imaging. The purpose of this investigation is to test the basic performance of a new dedicated breast-PET/CT.
methodsThe PET component consists of a rotating pair of detectors. Its performance was evaluated using the NEMA NU4-2008 protocols. The CT component utilizes a pulsed x ray source and flat panel detector mounted on the same gantry as the PET scanner. Its performance was assessed using specialized phantoms. The radiation dose to a breast during CT imaging was explored by the measurement of free-in-air kerma and air kerma measured at the center of a 16 cm-diameter PMMA cylinder. Finally, the combined capabilities of the system were demonstrated by imaging of a micro-hot-rod phantom.
resultsOverall, performance of the PET component is comparable to many pre-clinical and other dedicated breast-PET scanners. Its spatial resolution is 2.2 mm, 5 mm from the center of the scanner using images created with the single-sliced-filtered-backprojection algorithm. Peak NECR is 24.6 kcps; peak sensitivity is 1.36%; the scatter fraction is 27%. Spatial resolution of the CT scanner is 1.1 lp/mm at 10% MTF. The free-in-air kerma is 2.33 mGy, while the PMMA-air kerma is 1.24 mGy. Finally, combined imaging of a micro-hot-rod phantom illustrated the potential utility of the dual-modality images produced by the system.
conclusionThe basic performance characteristics of a new dedicated breast-PET/CT scanner are good, demonstrating that its performance is similar to current dedicated PET and CT scanners. The potential value of this system is the capability to produce combined duality-modality images that could improve detection of breast disease. The next stage in development of this system is testing with more advanced phantoms and human subjects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.