Evidence map›Paper›PMID 29389015›Full record

Trial reportJournal of child psychology and psychiatry, and allied disciplines2018

Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation.

Kathryn L Humphreys, Devi Miron, Katie A McLaughlin, Margaret A Sheridan, Charles A Nelson, Nathan A Fox, Charles H Zeanah

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of child psychology and psychiatry, and allied disciplines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
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  8. Review
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  10. Neurobiological Markers of Resilience to Early-Life Adversity During Adolescence.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Child Abuse and Neglect.Journal of the American Academy of Child and Adolescent Psychiatry · 2018
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Kathryn L HumphreysStanford University, Stanford, CA, USA.
Devi MironTulane University School of Medicine, New Orleans, LA, USA.
Katie A McLaughlinUniversity of Washington, Seatle, WA, USA.
Margaret A SheridanUniversity of North Carolina, Chapel Hill, Chapel Hill, NC, USA.
Charles A NelsonBoston Children's Hospital/Harvard Medical School, Boston, MA, USA.
Nathan A FoxUniversity of Maryland, College Park, MD, USA.
Charles H ZeanahTulane University School of Medicine, New Orleans, LA, USA.
Tulane University · USBoston Children's Hospital · USStanford University · USUniversity of Maryland, College Park · USUniversity of North Carolina at Chapel Hill · USWashington Sea Grant · US

Funding

The Relation Between Early Psychosocial Deprivation and Mental Health at 12 YearsR01MH091363 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI FOX, NATHAN A, NELSON, CHARLES ALEXANDER · 2010 to 2024
$9.2M
Mouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI POMEROY, SCOTT LOREN · 2016 to 2020
$5.2M
NICHD NIH HHS U54 HD090255NIMH NIH HHS R01 MH091363
6 · The paper itself

Abstract

backgroundExperiences in early life lay the foundation for later development and functioning. Severe psychosocial deprivation, as experienced by children in early institutional care, constitutes an adverse experience with long-term negative consequences. The Bucharest Early Intervention Project sought to examine the effects of foster care as an alternative to institutional care for abandoned infants in Romanian institutions.

methodsAt a mean age of 22 months, institutionalized children were randomized to foster care or care as usual. At age 12 years, we followed-up with 98 of these children (50 randomized to foster care), as well as assessed 49 never institutionalized comparison children. Adaptive functioning was assessed across seven domains-mental health, physical health, substance use, risk-taking behavior, family relations, peer relations, and academic performance. Children at or above the threshold for adaptive functioning in at least six of seven domains were classified as having overall adaptive functioning in early adolescence.

resultsAmong all children who had experienced severe early deprivation, 40% exhibited adaptive functioning. Children randomized to foster care were significantly more likely to exhibit adaptive functioning at age 12 years than children in the care as usual condition (56% vs. 23%). In support of external validity, children who met the threshold for adaptive functioning at age 12 years had higher IQs and were more physiologically responsive to stress. Among children randomized to foster care, children placed prior to age 20 months were more likely to meet the threshold for adaptive functioning than those placed after this age (79% vs. 46%).

conclusionsThis study provides causal evidence that placing children into families following severe deprivation increases the likelihood of adaptive functioning in early adolescence.

Indexed as

Adaptation, PsychologicalPsychosocial DeprivationSocial SkillsAdolescentChildChild BehaviorChild, InstitutionalizedChild, PreschoolFemaleFollow-Up StudiesFoster Home CareHumansInfantIntelligenceMaleRomaniaadaptive functioningfoster careInstitutional careresilience

Identifiers

PMID29389015
PMCPMC6214343
OpenAlexW2790801371

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.