Evidence map›Paper›PMID 29388902›Full record

ArticleJournal of personality disorders2018

Attachment-Related Regulatory Processes Moderate the Impact of Adverse Childhood Experiences on Stress Reaction in Borderline Personality Disorder.

Johannes C Ehrenthal, Kenneth N Levy, Lori N Scott, Douglas A Granger

Abstract read
In one paragraph

Article in Journal of personality disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Observational
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Johannes C EhrenthalDepartment of Psychology, Pennsylvania State University.
Kenneth N LevyDepartment of Psychology, Pennsylvania State University.
Lori N ScottDepartment of Psychiatry, University of Pittsburgh School of Medicine.
Douglas A GrangerInstitute for Interdisciplinary Salivary Bioscience Research, University of California at Irvine.

Funding

Aggression, Emotion, and Borderline Personality Disorder Features in WomenK01MH101289 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCOTT, LORI N · 2013 to 2017
$782k
Mood and Reactivity in Borderline Personality DisorderF31MH081395 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI SCOTT, LORI N · 2007 to 2009
$83k
NIMH NIH HHS F31 MH081395NIMH NIH HHS K01 MH101289NIMH NIH HHS L30 MH098303
6 · The paper itself

Abstract

In this study, the authors explored whether attachment insecurity moderates the effects of adverse childhood experiences on stress reactivity in the context of borderline personality disorder (BPD). Participants were 113 women (39 with BPD, 15 with some BPD criteria present, 59 without any BPD symptoms) who participated in the Trier Social Stress Test. Saliva samples were collected before and after the stressor and assayed for salivary alpha-amylase (sAA) and cortisol. Adverse childhood experiences were measured using the Childhood Trauma Questionnaire, and attachment by the Experiences in Close Relationships-Revised questionnaire. Results revealed that attachment avoidance and a combination of more adverse childhood experiences and attachment insecurity resulted in higher sAA levels and differences in reactivity to the stressor. Interactions between attachment anxiety and adverse childhood experiences were related to blunted cortisol reactivity. The results suggest that the influence of adverse childhood experiences on stress regulation in BPD may be moderated by attachment-related regulatory processes.

Indexed as

Adverse Childhood ExperiencesAdultAnxietyBorderline Personality DisorderCase-Control StudiesChildFemaleHumansHydrocortisoneReactive Attachment DisorderSalivaSalivary alpha-AmylasesSelf ReportStress, PsychologicalSurveys and QuestionnairesYoung AdultHydrocortisoneSalivary alpha-Amylases

Identifiers

PMID29388902
PMCPMC5798009

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.