Evidence map›Paper›PMID 29388807›Full record

ArticleThe British journal of radiology2018

Spectrum of MRI brain lesion patterns in neuromyelitis optica spectrum disorder: a pictorial review.

Kevin Yuqi Wang, Justin Chetta, Pavit Bains, Anthony Balzer, John Lincoln, Tomas Uribe, Christie M Lincoln

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Factors for Rituximab Refractoriness in AQP4-IgG+ NMOSD: A Cohort Study.Annals of clinical and translational neurology · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Neuromyelitis Optica Spectrum Disorder: A Case Report.International medical case reports journal · 2021
    Article
  10. Update on neuromyelitis optica spectrum disorder.Current opinion in ophthalmology · 2020
    Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kevin Yuqi Wang1 Department of Radiology, Baylor College of Medicine , Houston, TX , USA.
Justin Chetta1 Department of Radiology, Baylor College of Medicine , Houston, TX , USA.
Pavit Bains2 Radiology Associates of North Texas , Fort Worth, TX , USA.
Anthony Balzer1 Department of Radiology, Baylor College of Medicine , Houston, TX , USA.
John Lincoln3 Department of Neurology, The University of Texas Health Science Center at Houston , Houston, TX , USA.
Tomas Uribe1 Department of Radiology, Baylor College of Medicine , Houston, TX , USA.
Christie M Lincoln1 Department of Radiology, Baylor College of Medicine , Houston, TX , USA.
Baylor College of Medicine · USRadiology Associates · USThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromyelitis optica is a neurotropic autoimmune inflammatory disease of the central nervous system traditionally thought to exclusively involve the optic nerves and spinal cord. With the discovery of the disease-specific aquaporin-4 antibody and the increasing recognition of clinical and characteristic imaging patterns of brain involvement in what is now termed neuromyelitis optica spectrum disorder (NMOSD), MRI now plays a greater role in diagnosis of NMOSD based on the 2015 consensus criteria and in distinguishing it from other inflammatory disorders, particularly multiple sclerosis (MS). Several brain lesion patterns are highly suggestive of NMOSD, whereas others may serve as red flags. Specifically, long corticospinal lesions, hemispheric cerebral white matter lesions and periependymal lesions in the diencephalon, dorsal brainstem and white matter adjacent to lateral ventricles are typical of NMOSD. In contrast, juxtacortical, cortical, or lesions perpendicularly oriented to the surface of the lateral ventricle suggests MS as the diagnosis. Ultimately, a strong recognition of the spectrum of MRI brain findings in NMOSD is essential for accurate diagnosis, and particularly in differentiating from MS. This pictorial review highlights the spectrum of characteristic brain lesion patterns that may be seen in NMOSD and further delineates findings that may help distinguish it from MS.

Indexed as

AdultAgedBrainBrain StemCerebral AqueductCerebral VentriclesDiencephalonFemaleHumansLateral VentriclesMagnetic Resonance ImagingMaleMiddle AgedNeuromyelitis OpticaPyramidal TractsWhite Matter

Identifiers

PMID29388807
PMCPMC6223278
OpenAlexW2787301473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.