Evidence map›Paper›PMID 29388770›Full record

ArticleJournal of medicinal chemistry2018

A Dual Reporter Iodinated Labeling Reagent for Cancer Positron Emission Tomography Imaging and Fluorescence-Guided Surgery.

Zhi Lu, Truc Thuy Pham, Vineeth Rajkumar, Zilin Yu, R Barbara Pedley, Erik Årstad, John Maher, Ran Yan

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. The chemical tool-kit for molecular imaging with radionuclides in the age of targeted and immune therapy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. New Developments in Dual-Labeled Molecular Imaging Agents.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Zhi LuDepartment of Nuclear Medicine, First Affiliated Hospital of Dalian Medical University , Dalian 116020, People's Republic of China.
Truc Thuy PhamSchool of Imaging Sciences and Biomedical Engineering, King's College London , St. Thomas' Hospital, London SE1 7EH, United Kingdom.
Vineeth RajkumarUCL Cancer Institute, University College London , 72 Huntley Street, London WC1E 6BT, United Kingdom.
Zilin YuSchool of Imaging Sciences and Biomedical Engineering, King's College London , St. Thomas' Hospital, London SE1 7EH, United Kingdom.
R Barbara PedleyUCL Cancer Institute, University College London , 72 Huntley Street, London WC1E 6BT, United Kingdom.
Erik ÅrstadInstitute of Nuclear Medicine and Department of Chemistry, University College London , 235 Euston Road (T-5), London NW1 2BU, United Kingdom.
John MaherSchool of Cancer and Pharmaceutical Studies, Guy's Hospital, King's College London , Third Floor Bermondsey Wing, Great Maze Pond, London SE1 9RT, United Kingdom.
Ran YanSchool of Imaging Sciences and Biomedical Engineering, King's College London , St. Thomas' Hospital, London SE1 7EH, United Kingdom.ORCID 0000-0002-0303-3196
St Thomas' Hospital · GBUniversity College London · GBGuy's Hospital · GB

Funding

Cancer Research UK 16463Cancer Research UK 21030Medical Research Council G1001497Wellcome Trust
6 · The paper itself

Abstract

The combination of early diagnosis and complete surgical resection offers the greatest prospect of curative cancer treatment. An iodine-124/fluorescein-based dual-modality labeling reagent,

Indexed as

AnimalsAntibodies, MonoclonalHeterograftsHumansImmunoconjugatesIodine RadioisotopesMiceNeoplasmsOptical ImagingPositron-Emission TomographyA5B7 monoclonal antibodyAntibodies, MonoclonalImmunoconjugatesIodine-124Iodine Radioisotopes

Identifiers

PMID29388770
PMCPMC5847118
OpenAlexW2787812418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.