ReviewPediatric health, medicine and therapeutics2017
Functional constipation in children: challenges and solutions.
Review in Pediatric health, medicine and therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bladder and Bowel Dysfunction in Children
Evaluating the Effectiveness of the LiveSpo® Preg-Mom and LiveSpo® KIDS Spore Probiotics in Supporting the Reduction of Constipation, Anorexia, and Slow Weight Gain in Children Aged 24-60 Months
Who cites it
33 citing papers in PubMed, 109 citations in OpenAlex.
- Laser acupuncture improving functional chronic constipation in children: a randomized controlled trial.Lasers in medical science · 2023Trial
- The use of two Comfort Young Child Formulas in the dietary management of toddlers with functional constipation: a randomized controlled trial.BMC pediatrics · 2022Trial
- Trial
- Bowel Habits and Functional Constipation in Healthy Children-A Longitudinal Birth-Cohort Study.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Evaluating the role of the Bristol stool chart in diagnosing functional constipation in pediatric populations.World journal of clinical pediatrics · 2026Article
- Dolichocolon is common in pediatric gastroenterology patients with constipation and associated complaints.Journal of pediatric gastroenterology and nutrition · 2026Article
- Prevalence of Functional Constipation in Children with Down Syndrome: A Study Conducted at a General Pediatrics Service.Biomedicines · 2026Article
- Association Between Functional Constipation and Growth Status in Children Based on Anthropometric Indices.Pediatric gastroenterology, hepatology & nutrition · 2025Article
- Forensic considerations in cases of fatal constipation.Forensic science, medicine, and pathology · 2025Review
- Weaning strategies for osmotic laxatives in children with functional constipation: a pilot multicenter randomized controlled trial.Translational pediatrics · 2025Article
- Investigating the effects of using Tecar therapy with biofeedback compared to biofeedback alone in the treatment of fecal incontinence in children aged 4 to 16 years: a randomized clinical trial study.Gastroenterology and hepatology from bed to bench · 2025Article
- Anxiety and depression in pediatric patients with disorder of brain-gut interaction: the role of diarrhea and abdominal pain as key determinants.Frontiers in pediatrics · 2025Article
- Long-term implications of a multidisciplinary tube-weaning program: Parental perspectives.JPGN reports · 2024Article
- Exploring Community Perspectives on Functional Paediatric Habitual Constipation.International journal of environmental research and public health · 2024Article
- Article
- Multicentre Study Into the Use of Polyethylene Glycol With Electrolytes Over at Least 6 Months to Treat Constipation in Paediatric Populations.JPGN reports · 2023Article
- Gutted: constipation in children with chronic kidney disease and on dialysis.Pediatric nephrology (Berlin, Germany) · 2023Review
- Article
- Impact of Probiotics on the Prevention and Treatment of Gastrointestinal Diseases in the Pediatric Population.International journal of molecular sciences · 2023Review
- Probiotics for functional constipation in children: an overview of overlapping systematic reviews.Frontiers in cellular and infection microbiology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review intends to update what is known about and what is still a challenge in functional constipation (FC) in children regarding epidemiology, pathophysiology, diagnosis, and management. Although FC is a common childhood problem, its global burden remains unknown as data from parts of the world are missing. Another problem is that there is a large variation in prevalence due to differences in study methods and defining age groups. The pathophysiology of FC remains unclear to date but is probably multifactorial. Withholding behavior is likely to be the most important factor in toddlers and young children. Genetics may also play a role since many patients have positive family history, but mutations in genes associated with FC have not been found. Over the past years, different diagnostic criteria for FC in infants and children have been proposed. This year, Rome IV criteria have been released. Compared to Rome III, it eliminates two diagnostic criteria in children under the age of 4 who still wear diapers. Physical examination and taking a thorough medical history are recommended, but other investigations such as abdominal radiography, transabdominal recto-ultrasonography, colonic transit time, rectal biopsies, and colon manometry are not routinely recommended. Regarding treatment, guidelines recommend disimpaction and maintenance therapy with polyethylene glycol (PEG) with or without electrolytes. But experience shows that acceptability, adherence, and tolerance to PEG are still a challenge. Counseling of parents and children about causes of FC is often neglected. Recent studies suggest that behavior therapy added to laxative therapy improves the relief of symptoms. Further homogeneous studies, better-defined outcomes, and studies conducted in primary care are needed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.