SynthesisJournal of clinical and experimental neuropsychology2018
Meta-analysis of cognitive performance in fibromyalgia.
Synthesis in Journal of clinical and experimental neuropsychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 67 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Development of Complementary Tools for the Differential Diagnosis of Fibromyalgia Based on Cognitive Task Performance
Investigation of the Relationship Between Central Sensitization Symptoms and Cognitive Dysfunction in Patients With Fibromyalgia
Who cites it
67 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Effects of 36.5 Hz pulsed LASER acupuncture on pain and disease impact in fibromyalgia patients: A pilot randomized clinical trial.Clinical rheumatology · 2025Trial
- Effect of neuronavigated repetitive Transcranial Magnetic Stimulation on pain, cognition and cortical excitability in fibromyalgia syndrome.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Trial
- Longitudinal associations of pain and cognitive decline in community-dwelling older adults.Psychology and aging · 2022Trial
- Women's Ways of Coping With Chronic Widespread Pain-A Phenomenographic Study.Musculoskeletal care · 2026Article
- Pain hypervigilance is associated with daily-activity pain beyond resting pain in women with fibromyalgia: a cross-sectional observational study.Clinical rheumatology · 2026Observational
- A Brief Mindfulness Intervention for Pain Management in Fibromyalgia: A Single-arm Open-Label Study.Restorative neurology and neuroscience · 2026Article
- The genetics of fibromyalgia and its relationships to psychiatric and medical traits.Nature communications · 2026Article
- Fibromyalgia: Neuropsychological and Clinical Correlates in Suicidal Behavior Based on Ideation-to-Action Models-A Critical Review.Behavioral sciences (Basel, Switzerland) · 2026Review
- Effects of a Strength and Creative Dance Intervention on Brain Electrical Activity, Heart Rate Variability, and Dual-Task Performance in Women with Fibromyalgia: A Randomized Controlled Trial Protocol.Sports (Basel, Switzerland) · 2026Article
- Impact of cognitive behavioral therapy on attention in patients with fibromyalgia: a randomized controlled trial.Pain reports · 2026Article
- Cognitive Dysfunction in Fibromyalgia: Prevalence and Independent Predictors-A Case-Control Study Using the Montreal Cognitive Assessment Scale.Brain sciences · 2026Article
- Coenzyme Q10 Ameliorates Fibromyalgia-like Symptoms and Cognitive Deficits by Enhancing Hippocampal PGC-1α/FNDC5/BDNF Pathway in Reserpine-Treated Rats.Molecular neurobiology · 2025Article
- Association of nociplastic pain with executive function decline in a longitudinal cohort of middle-age adults: a prospective cohort study.British journal of anaesthesia · 2025Article
- Cognitive profiling in fibromyalgia patients using the MoCA.Irish journal of medical science · 2025Article
- Disentangling interoception and its links to cognitive functioning in fibromyalgia.Scientific reports · 2025Article
- Planning and Problem-Solving Impairments in Fibromyalgia: The Predictive Role of Updating, Inhibition, and Mental Flexibility.Journal of clinical medicine · 2025Article
- Heavy metals, noradrenaline/adrenaline ratio, and microbiome-associated hormone precursor metabolites: biomarkers for social behaviour, ADHD symptoms, and executive function in children.Scientific reports · 2025Article
- History of chronic pain and opioid use is associated with cognitive decline and mild cognitive impairment.Journal of the International Neuropsychological Society : JINS · 2025Article
- Neuropsychological Performance: How Mental Health Drives Attentional Function in University-Level Football Athletes.Sports (Basel, Switzerland) · 2025Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
introductionFibromyalgia is a condition with symptoms of pain, physical function difficulties, and emotional problems, but is also characterized by complaints of poor cognition (often called "FibroFog"). Over the last two decades, a number of studies have examined cognitive differences between individuals with and without fibromyalgia. The purpose of the current study was to conduct a quantitative synthesis of these differences across multiple cognitive domains.
methodFollowing Cochrane guidelines, we identified 37 eligible studies for analysis where persons with fibromyalgia (total n = 964) were compared to participants from age-matched control groups without fibromyalgia (total n = 1025) on a range of neuropsychological measures. Group differences between persons with fibromyalgia and healthy controls were examined for cognitive domains including processing speed, long- and short-term memory, and executive functions (inhibitory control, set shifting, updating, and accessing). Random-effect meta-analyses were conducted to determine effect sizes for these differences in cognitive performance.
resultsFibromyalgia was significantly and negatively associated with performance on all domains of cognitive function. The largest effect size was found for inhibitory control (g = 0.61), followed by memory (g = 0.51 for short-term, 0.50 for long-term memory). The smallest cognitive difference between those with fibromyalgia and controls was for set shifting (g = 0.30).
conclusionThese findings support the hypothesis that the self-reported cognitive impact of fibromyalgia is also found in objective neuropsychological measures. Routine screening for cognitive dysfunction in those with fibromyalgia may be warranted in addition to assessment of the traditional fibromyalgia symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.