ArticleBritish journal of clinical pharmacology2018
Argon attenuates multiorgan failure following experimental aortic cross-clamping.
Article in British journal of clinical pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Argon Attenuates Multiorgan Failure in Relation with HMGB1 Inhibition.International journal of molecular sciences · 2021Article
- The Role of Vaccinium Myrtillus in the Prevention of Renal Injury in an Experimental Model of Ruptured Abdominal Aortic Aneurysm.Brazilian journal of cardiovascular surgery · 2020Article
- Tea Grape Reduces Abdominal Aortic Occlusion-Induced Lung Injury.Brazilian journal of cardiovascular surgery · 2020Article
- Update of the organoprotective properties of xenon and argon: from bench to beside.Intensive care medicine experimental · 2020Review
- The effects of whortleberry on ischemia reperfusion-induced myocardial injury in rats.Turk gogus kalp damar cerrahisi dergisi · 2020Article
- Argon attenuates multiorgan failure following experimental aortic cross-clamping.British journal of clinical pharmacology · 2018Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsArgon has been shown to prevent ischaemic injuries in several scenarios of regional ischaemia. We determined whether it could provide a systemic effect in a model of multiorgan failure (MOF) induced by aortic cross-clamping.
methodsAnaesthetized rabbits were submitted to aortic cross-clamping (30 min) and subsequent reperfusion (300 min). They were either ventilated with oxygen-enriched air throughout the protocol [fraction of inspired oxygen (FiO
resultsCompared with control, shock was significantly attenuated in Argon-Total and Argon-Pre but not Argon-Post groups (e.g. cardiac output = 62±5 vs. 29 ± 5 ml min
conclusionArgon attenuated clinical and biological modifications of cardiovascular, renal and intestinal systems, but not the inflammatory response, after aortic cross-clamping. The window of administration was crucial to optimize organ protection.
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