Evidence map›Paper›PMID 29388128›Full record

ArticleAmbio2018

Modulators of mercury risk to wildlife and humans in the context of rapid global change.

Collin A Eagles-Smith, Ellen K Silbergeld, Niladri Basu, Paco Bustamante, Fernando Diaz-Barriga, William A Hopkins, Karen A Kidd, Jennifer F Nyland

Open access · hybridAbstract read
In one paragraph

Article in Ambio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 3 pooled it
21.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 3 syntheses or guidelines pooled it, 350 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Mercury-induced excitotoxicity in autism spectrum disorder: disruption of glutamatergic homeostasis and the therapeutic role of the selenium-glutathione axis.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 4 countries.

Collin A Eagles-SmithUS Geological Survey, 3200 SW Jefferson Way, Corvallis, OR, 97331, USA. ceagles-smith@usgs.gov.
Ellen K SilbergeldJohns Hopkin Bloomberg School of Public Health, 615 N. Wolfe Street, E6644, Baltimore, MD, 21205, USA.
Niladri BasuMcGill University, 204-CINE Building, Montreal, QC, H9X 3V9, Canada.
Paco BustamanteUniversity of La Rochelle, laboratory of Littoral Environment and Societies, Littoral Environnement et Sociétés (LIENSs), LIENSs UMR 7266 CNRS-Université de La Rochelle, 2 rue Olympe de Gouges, 17000, La Rochelle, France.
Fernando Diaz-BarrigaCenter for Applied Research in Environment and Health at, Universidad Autonoma de San Luis Potosi, Avenida Venustiano Carranza No. 2405, Col Lomas los Filtros Código Postal, 78214, San Luis Potosí, SLP, Mexico.
William A HopkinsDepartment of Fish and Wildlife Conservation, 310 West Campus Drive Virginia Tech, Cheatham Hall, Room 106 (MC 0321), Blacksburg, VA, 24061, USA.
Karen A KiddDepartment of Biology & School of Geography and Earth Sciences, McMaster University, 1280 Main Street W., Hamilton, ON, L8S 4K1, Canada.
Jennifer F NylandDepartment of Biological Sciences, 1101 Camden Ave, Salisbury, MD, 21801, USA.
Autonomous University of San Luis Potosí · MXCentre National de la Recherche Scientifique · FRJohns Hopkins University · USMcGill University · CAMcMaster University · CASalisbury University · USUnited States Geological Survey · USVirginia Tech · US

Funding

VARIATION IN BIOACCUMULATION AND BIOMAGNIFICATION OF METALS IN NORTHERN US LAKESP42ES007373 · NIEHS · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 1995 to 2019
$52.0M
Integrating Mercury Research and Policy in a Changing WorldR13ES028077 · NIEHS · DARTMOUTH COLLEGE · PI CHEN, CELIA Y · 2017 to 2017
$22k
NIEHS NIH HHS P42 ES007373NIEHS NIH HHS R13 ES028077
6 · The paper itself

Abstract

Environmental mercury (Hg) contamination is an urgent global health threat. The complexity of Hg in the environment can hinder accurate determination of ecological and human health risks, particularly within the context of the rapid global changes that are altering many ecological processes, socioeconomic patterns, and other factors like infectious disease incidence, which can affect Hg exposures and health outcomes. However, the success of global Hg-reduction efforts depends on accurate assessments of their effectiveness in reducing health risks. In this paper, we examine the role that key extrinsic and intrinsic drivers play on several aspects of Hg risk to humans and organisms in the environment. We do so within three key domains of ecological and human health risk. First, we examine how extrinsic global change drivers influence pathways of Hg bioaccumulation and biomagnification through food webs. Next, we describe how extrinsic socioeconomic drivers at a global scale, and intrinsic individual-level drivers, influence human Hg exposure. Finally, we address how the adverse health effects of Hg in humans and wildlife are modulated by a range of extrinsic and intrinsic drivers within the context of rapid global change. Incorporating components of these three domains into research and monitoring will facilitate a more holistic understanding of how ecological and societal drivers interact to influence Hg health risks.

Indexed as

Food ChainRiskAnimalsAnimals, WildEnvironmental MonitoringHumansMercuryWater Pollutants, ChemicalMercuryWater Pollutants, ChemicalASGMBiomagnificationFisheriesImmunotoxicityInvasive speciesMicrobiomeSelenium

Identifiers

PMID29388128
PMCPMC5794686
OpenAlexW2785784801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.