Evidence map›Paper›PMID 29388037›Full record

ArticleSkeletal radiology2018

Pseudotumor in metal-on-metal hip arthroplasty: a comparison study of three grading systems with MRI.

C Smeekes, B J M Schouten, M Nix, B F Ongkiehong, R Wolterbeek, B C H van der Wal, R G H H Nelissen

Abstract readComparative Study
In one paragraph

Article in Skeletal radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. "Squeaky Hip": Are Noises Important?Arthroplasty today · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Semi-quantitative histology confirms that the macrophage is the predominant cell type in metal-on-metal hip tissues.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

C SmeekesDepartment of Orthopaedics, Leiden University Medical Centre, 9600, 2300, RC, Leiden, The Netherlands. c.smeekes@lumc.nl.
B J M SchoutenDepartment of Radiology & Nuclear Medicine, Maasstad Hospital, Rotterdam, The Netherlands.
M NixDepartment of Radiology, Meander Medical Centre, Amersfoort, The Netherlands.
B F OngkiehongDepartment of Orthopaedics, Meander Medical Centre, Amersfoort, The Netherlands.
R WolterbeekDepartment of Medical Statistics and Bioinformatics, Leiden University Medical Centre, Leiden, The Netherlands.
B C H van der WalDepartment of Orthopaedics, Meander Medical Centre, Amersfoort, The Netherlands.
R G H H NelissenDepartment of Orthopaedics, Leiden University Medical Centre, 9600, 2300, RC, Leiden, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePseudotumors, a well-known complication of metal-on-metal total hip arthroplasty (MoM THA), are well identified on metal artifact-reducing sequences magnetic resonance imaging (MARS-MRI). Several MRI grading systems are described in the orthopedic literature, but their validity is unknown in large clinical studies. Our study was undertaken to describe the classification of pseudotumors in a preselected cohort divided into high- and low-risk patients, using three pseudotumor grading systems applied on MARS-MRI, and to determine the interobserver reliability of the grading systems. PATIENTS AND

methodsA retrospective study was performed on 377 consecutive patients (240 MRI scans) treated with an M2a-38 and Taperloc stem combination (Biomet, Warsaw, IN, USA). Patients were divided into a high-risk and a low-risk group based on previous published risk factors. Two observers determined the presence of pseudotumors using three different pseudotumor grading systems for classifying MARS-MRI results.

resultsThe prevalence of pseudotumors as determined with MARS-MRI was 59% in our high-risk group, 0% in the low-risk group and 43% in the control group. Serum cobalt values were increased in the high-risk group. The kappa values of the Anderson, Hauptfleisch and Matthies grading system scores were 0.43, 0.44, and 0.49 respectively.

conclusionsHigh-risk patients are at a high risk for pseudotumor development. No pseudotumor development was found in low-risk patients. Interobserver reliability scored best with the Matthies system, but all three grading systems showed only a moderate agreement.

Indexed as

Arthroplasty, Replacement, HipMagnetic Resonance ImagingFemaleGranuloma, Plasma CellHip ProsthesisHumansMaleMetal-on-Metal Joint ProsthesesMiddle AgedObserver VariationProsthesis DesignReproducibility of ResultsRetrospective StudiesRiskClassificationGrading systemInterobserver reliabilityMARS-MRIMoMPseudotumorTHA

Identifiers

PMID29388037
PMCPMC6003970

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.