ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018
Fertility information needs and concerns post-treatment contribute to lowered quality of life among young adult female cancer survivors.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 3 of them syntheses that pooled it.
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Who cites it
75 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Limited Recommendations and Evidence for Timing and Frequency of Anti-Mullerian Hormone Screening in Female Pediatric Cancer Survivors: A Systematic Review from the Pediatric and Adolescent Committee of the Oncofertility Consortium.Journal of adolescent and young adult oncology · 2025Pooled it
- Decision aids for cancer survivors' engagement with survivorship care services after primary treatment: a systematic review.Journal of cancer survivorship : research and practice · 2024Pooled it
- Fertility discussions and concerns in childhood cancer survivors, a systematic review for updated practice.Cancer medicine · 2023Pooled it
- Let's TOC Fertility: A stepped wedge cluster randomized controlled trial of the Telehealth Oncofertility Care (TOC) intervention in children, adolescent and young adult cancer survivors.Contemporary clinical trials · 2024Trial
- A randomized pilot study of mindfulness-based stress reduction in a young adult cancer sample: Feasibility, acceptability, and changes in patient reported outcomes.Psycho-oncology · 2020Trial
- Metacognitions and Reproductive Concerns in Testicular Cancer Patients of Reproductive Age: The Mediating Role of Fear of Progression.Cancer medicine · 2026Article
- Potential profile analysis of reproductive concerns and influencing factors among testicular cancer patients of reproductive age.BMC cancer · 2026Article
- Suboptimal quality of female oncofertility care is associated with lowered quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Fertility Preservation Services for Adolescents and Young Adults: 2022 National Cancer Institute Community Oncology Research Program Landscape Assessment.JCO oncology practice · 2026Article
- Fertility preservation in women with cancer: shared decision-making and the essential role of nurses.Women's health nursing (Seoul, Korea) · 2025Article
- Fertility Concerns and Outcomes Among Adolescent and Young Adult Males With Melanoma Receiving Immunotherapy: A Mixed-Methods Study.Cancer medicine · 2025Article
- Fertility preservation and mental health among cancer patients of reproductive age.Fertility and sterility · 2025Review
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- A life put on hold? Navigating fertility-related considerations after cancer in adolescence and young adulthood (AYA).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Article
- Mapping the Unmet Informational Needs of Young Portuguese Female Cancer Survivors: Psychometric Validation of a Multidimensional Scale.Healthcare (Basel, Switzerland) · 2025Article
- Perceived impact of a decision-aid and planning tool for family building after cancer for young adult female cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Online discussions about cancer and fertility: an analysis of Reddit threads.Journal of assisted reproduction and genetics · 2025Article
- Ovarian function and response to gonadotropins after prolonged perfusion of whole ewe ovaries in a bioreactor.Journal of assisted reproduction and genetics · 2025Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundCancer treatment may lead to premature menopause and infertility. Young adult female cancer survivors (YAFCS) are often concerned about their fertility and future family-building options, but research is limited on how concerns may affect more general quality of life (QOL) domains. This study examined how fertility factors relate to QOL among YAFCS who received gonadotoxic therapy.
methodA national sample of YAFCS completed an online, anonymous survey. The survey included investigator-designed questions about perceived fertility information needs (five items; Cronbach's α = .83) and general QOL (four items; α = .89), the Reproductive Concerns after Cancer Scale (RCACS) and Decisional Conflict Scale (DCS). Analyses included Pearson's correlation, t tests, and stepwise regression.
resultsParticipants (N = 314) were an average of 30 years old (SD = 4.1) and 5 years (SD = 5.4) post-treatment; 31% reported being infertile and 19% had undergone fertility preservation (FP). Overall, QOL was relatively high (M = 7.3, SD = 1.9, range 0-10) and did not vary by fertility status (t[272] = .743, p = .46), prior FP (t[273] = .53, p = .55) or sociodemographic/clinical factors (p's > .05) except socioeconomic indicators (p's < .05).In separate models, greater unmet fertility information needs (β = - .19, p = .004) and, among fertile women, greater reproductive concerns (β = - .26, p = .001) related to lower QOL. Among fertile women without prior FP, greater decisional distress about future FP related to lower QOL (β = - .19, p = .03).
conclusionsThese preliminary findings suggest that unaddressed fertility information needs, concerns, and decision distress may affect general QOL among post-treatment YAFCS who hope to have children in the future. Future work should identify ways to optimally incorporate fertility counseling and support resources into survivorship care programs, including referrals to reproductive specialists as appropriate.
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