Evidence map›Paper›PMID 29387919›Full record

ArticleJournal of mathematical biology2018

Extinction times in the subcritical stochastic SIS logistic epidemic.

Graham Brightwell, Thomas House, Malwina Luczak

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In one paragraph

Article in Journal of mathematical biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Key questions for modelling COVID-19 exit strategies.Proceedings. Biological sciences · 2020
    Pooled it
  2. Article
  3. Predicting population extinction in lattice-based birth-death-movement models.Proceedings. Mathematical, physical, and engineering sciences · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Graham BrightwellDepartment of Mathematics, London School of Economics, London, UK.
Thomas HouseSchool of Mathematics, University of Manchester, Manchester, UK.ORCID 0000-0001-5835-8062
Malwina LuczakSchool of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia. mluczak@unimelb.edu.au.ORCID 0000-0002-9451-8825

Funding

CELL RADIATION RESPONSE AT LOW DOSE RATESR01CA033701 · NCI · COLORADO STATE UNIVERSITY-FORT COLLINS · PI ELKIND, MORTIMER M · 1985 to 1987
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Engineering and Physical Sciences Research Council EP/J004022/2Engineering and Physical Sciences Research Council EP/N033701/1
6 · The paper itself

Abstract

Many real epidemics of an infectious disease are not straightforwardly super- or sub-critical, and the understanding of epidemic models that exhibit such complexity has been identified as a priority for theoretical work. We provide insights into the near-critical regime by considering the stochastic SIS logistic epidemic, a well-known birth-and-death chain used to model the spread of an epidemic within a population of a given size N. We study the behaviour of the process as the population size N tends to infinity. Our results cover the entire subcritical regime, including the "barely subcritical" regime, where the recovery rate exceeds the infection rate by an amount that tends to 0 as [Formula: see text] but more slowly than [Formula: see text]. We derive precise asymptotics for the distribution of the extinction time and the total number of cases throughout the subcritical regime, give a detailed description of the course of the epidemic, and compare to numerical results for a range of parameter values. We hypothesise that features of the course of the epidemic will be seen in a wide class of other epidemic models, and we use real data to provide some tentative and preliminary support for this theory.

Indexed as

Models, BiologicalBasic Reproduction NumberCommunicable DiseasesComputer SimulationDisease SusceptibilityEpidemicsHumansLogistic ModelsMarkov ChainsMathematical ConceptsPopulation DensityStochastic ProcessesTime FactorsBirth-and-death chainNear-critical epidemicStochastic SIS logistic epidemicTime to extinction

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.