Evidence map›Paper›PMID 29387814›Full record

ArticleBiochemistry and biophysics reports2018

The role of Gα

Hirosato Mashima, Noboru Watanabe, Masanari Sekine, Satohiro Matsumoto, Takeharu Asano, Kazuhito Yuhashi, Noriyoshi Sagihara, Shunsuke Urayoshi, Takeshi Uehara, Junichi Fujiwara and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Hirosato MashimaDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Noboru WatanabeDepartment of Gastroenterology, Akita University Graduate School of Medicine, Akita 010-8543, Japan.
Masanari SekineDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Satohiro MatsumotoDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Takeharu AsanoDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Kazuhito YuhashiDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Noriyoshi SagiharaDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Shunsuke UrayoshiDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Takeshi UeharaDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Junichi FujiwaraDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Takehiro IshiiDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Rumiko TsuboiDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Hiroyuki MiyataniDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Hirohide OhnishiDepartment of Gastroenterology, Saitama Medical Center, Jichi Medical University, Saitama 330-8503, Japan.
Jichi Medical University · JPJichi Medical University Saitama Medical Center · JPAkita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal homeostasis and the coordinated actions of digestion, absorption and excretion are tightly regulated by a number of gastrointestinal hormones. Most of them exert their actions through G-protein-coupled receptors. Recently, we showed that the absence of Gα

Indexed as

Ab, antibodyACh, acetylcholineAtoh1, atonal homolog 1CCK2R, cholecystokinin-2 receptorCCK, cholecystokininDKO, double knock-outEnterocyteGIP, glucose-dependent insulinotropic polypeptideGLP-1, glucagon-like-peptide-1GPCR, G-protein coupled receptorGα11GαqHE, hematoxylin and eosinIEC, intestinal epithelial cellmAChR, muscarinic acetylcholine receptorNICD, Notch1 intracellular cytoplasmic domainNotchProliferationqPCR, quantitative real-time PCRsiRNA, small interfering RNATA, transit amplifyingTcf1, T-cell factor 1VIP, vasoactive intestinal peptideWnt/β-catenin

Identifiers

PMID29387814
PMCPMC5789759
OpenAlexW2792027017

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.