Mandibular Involvement in Recurrent Multifocal Osteomyelitis Associated with SAPHO Syndrome.

Igor-Moreira Hazboun, Thiago-Pires Brito, Vanessa-Gonçalves Silva, Carlos-Eduardo-Monteiro Zappelini, Leopoldo-Nizam Pfeilsticker

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Article in Iranian journal of otorhinolaryngology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

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1 · What the graph read from it

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2 · The registry

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0 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

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5 · Who and what money

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5 authors at 1 institution in 1 country.

Igor-Moreira HazbounDepartment of Otolaryngology Head and Neck, State University of Campinas, Faculty of Medical Sciences, Campinas, Sao Paulo, Brazil.

Thiago-Pires BritoDepartment of Otolaryngology Head and Neck, State University of Campinas, Faculty of Medical Sciences, Campinas, Sao Paulo, Brazil.

Vanessa-Gonçalves SilvaDepartment of Otolaryngology Head and Neck, State University of Campinas, Faculty of Medical Sciences, Campinas, Sao Paulo, Brazil.

Carlos-Eduardo-Monteiro ZappeliniDepartment of Otolaryngology Head and Neck, State University of Campinas, Faculty of Medical Sciences, Campinas, Sao Paulo, Brazil.

Leopoldo-Nizam PfeilstickerOtorhinolaryngologist, Coordinator of Ambulatory Surgery and Maxillofacial Traumatology, State University of Campinas, Faculty of Medical Sciences, Sao Paulo, Brazil.

Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSAPHO syndrome is defined as the association of a group of rare sterile osteoarticular disorders and inflammatory skin diseases whose etiology, although not yet determined, probably involves genetic, immunological and infectious mechanisms. The recurrent multifocal osteomyelitis, an inflammatory disease, can be associated with this syndrome even as a single event. CASE REPORT: A case of a young female patient, with a definite diagnosis of SAPHO and an inflammatory mandibular atypical disease for which therapeutic options with immunosuppressants were being used, is reported. The adverse evolution of the clinical conditions led to the hypothesis that the patient suffered from associated mandibular odontogenic bacterial osteomyelitis. The extraction of all teeth was recommended. After our evaluation, we recommended a conservative treatment, and after 2 months of treatment with an endovenous antibiotic, the patient showed improvement of clinical and laboratory results.

conclusionEarly diagnosis is necessary to avoid successive and unnecessary tooth loss in the treatment of chronic osteomyelitis mandibular.

Indexed as

Mandibular involvementOsteomyelitisSAPHO syndrome

Identifiers

PMID29387665

PMCPMC5787656

OpenAlexW2782499815

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