Evidence map›Paper›PMID 29387554›Full record

ArticleAsian journal of urology2017

Testosterone replacement maintains smooth muscle content in the corpus cavernosum of orchiectomized rats.

Graziele Halmenschlager, Ernani Luis Rhoden, Gabriela Almeida Motta, Lucas Sagrillo Fagundes, Jorge Luiz Medeiros, Rosalva Meurer, Cláudia Ramos Rhoden

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Asian journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. A low androgen state impairs erectile function by suppressingTranslational andrology and urology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Graziele HalmenschlagerCentro Universitário Ritter dos Reis (UniRitter) and Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA) - PPG Ciências da Saúde, Porto Alegre, RS, Brazil.
Ernani Luis RhodenDepartment of Urology at Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Urologist at Irmandade Santa Casa de Misericórdia de Porto Alegre (ISCMPA) and Hospital Moinhos de Vento de Porto Alegre (HMV), Porto Alegre, RS, Brazil.
Gabriela Almeida MottaUniversidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA) - PPG Ciências da Saúde-Porto Alegre, RS, Brazil.
Lucas Sagrillo FagundesINRS Institut Armand Frappier (Universit. du Québec) and BioMed Research Center Laval, Quebec, Canada.
Jorge Luiz MedeirosLaboratory of Morphometry, Metabolism, and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Rosalva MeurerUniversidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA) - PPG Ciências da Saúde-Porto Alegre, RS, Brazil.
Cláudia Ramos RhodenUniversidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA) - PPG Ciências da Saúde-Porto Alegre, RS, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effects of testosterone (T) on the maintenance of corpus cavernosum (CC) structure and apoptosis.

methodsAnimals were divided into three groups: sham operation group (

resultsT levels decreased in Orchiec + oily vehicle when compared to sham operation and Orchiec + T groups (

conclusionNormal testosterone levels maintain CC smooth muscle content and do not influence elastic fibers, collagen content and apoptotic index. Further studies should be performed in order to investigate the mechanisms by which androgen mediates its effects on CC structure.

Indexed as

Androgen deprivationCorpus cavernosumHistomorphometryHypogonadismTestosterone replacement

Identifiers

PMID29387554
PMCPMC5773047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.