Evidence map›Paper›PMID 29387272›Full record

ArticleThe open medicinal chemistry journal2017

Effects on Sperms' Quality of Selegiline in Aged Rats.

Huba Kalász, Julianna Thuróczy, Gellért Karvaly, Lajos Balogh, István Gyertyán, Edit Tóth-Molnár, Ernest Adeghate, Kornélia Tekes

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The open medicinal chemistry journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Huba KalászDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Nagyvárad tér 4, Hungary.
Julianna ThuróczyAnimal Health Center Budafok, H-1221 Budapest, Kossuth Lajos Str. 52. Hungary.
Gellért KarvalyDepartment of Laboratory Medicine, Semmelweis University, 1089 Budapest, Nagyvárad tér 4, Hungary.
Lajos BaloghNational "FJC" Research Institute for Radiobiology and Radiohigiene, H-1221 Budapest, Anna Str. 5. Hungary.
István GyertyánDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Nagyvárad tér 4, Hungary.
Edit Tóth-MolnárDepartment of Ophthalmology, University of Szeged, 6720 Szeged, Korányi fasor 10- 11, Hungary.
Ernest AdeghateDepartment of Anatomy, United Arab Emirates University, P.O.Box 17666, Al Ain, United Arab Emirates.
Kornélia TekesDepartment of Pharmacodynamics, Semmelweis University, 1089 Budapest, Nagyvárad tér 4, Hungary.
Semmelweis University · HUBuda Health Center · HUFrédéric Joliot-Curie National Research Institute for Radiobiology and Radiohygiene · HUUniversity of Szeged · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelegiline is used to treat Parkinsonian patients. Other indications of its use have recently been discovered.

objectiveScouting special and beneficial side effects of selegiline treatment.

methodTwo-year old male Wistar rats were daily treated with 0.25 mg/kg of selegiline s.c. (subcutaneous injection). The rats were sacrificed following a four-weeks' treatment.

resultsMass of testes, number of sperms, progressive motility of sperms, and their viability definitely increased.

conclusionSelegiline can successfully be used to stop/counterbalance certain symptoms of aging.

Indexed as

Aged-ratsCortisolDopamineSelegilineSemenSpermTestisTestosterone

Identifiers

PMID29387272
PMCPMC5748828
OpenAlexW2768428589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.