Evidence map›Paper›PMID 29387234›Full record

ArticleOncology letters2018

Cadherin 17 is related to recurrence and poor prognosis of cytokeratin 19-positive hepatocellular carcinoma.

Chao-Wei Lee, Sey-En Lin, Hsin-I Tsai, Po-Jung Su, Chia-Hsun Hsieh, Yung-Chia Kuo, Chang-Mu Sung, Cheng-Yu Lin, Chi-Neu Tsai, Ming-Chin Yu

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  3. Cadherin 17 and digestive cancers: from diagnostic to therapeutic opportunities.Journal of experimental & clinical cancer research : CR · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Chao-Wei LeeDepartment of Surgery, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan, R.O.C.
Sey-En LinDepartment of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan, R.O.C.
Hsin-I TsaiCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan, R.O.C.
Po-Jung SuCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan, R.O.C.
Chia-Hsun HsiehCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan, R.O.C.
Yung-Chia KuoCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan, R.O.C.
Chang-Mu SungCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan, R.O.C.
Cheng-Yu LinDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan, R.O.C.
Chi-Neu TsaiGraduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan 33302, Taiwan, R.O.C.
Ming-Chin YuDepartment of Surgery, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan, R.O.C.
Chang Gung University of Science and Technology · TWChang Gung Memorial Hospital · TWChang Gung University · TWWan Fang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A previous study demonstrated that cytokeratin 19 (CK19) expression in hepatocellular carcinoma (HCC) is an indicator of HCC invasiveness, including lymph node metastasis (LNM), tumor infiltration/non-encapsulation and poor prognosis. The exact mechanism by which CK19 expression results in poor prognosis remains unclear. Through the use of an Affymetrix U133A oligonucleotide microarray [20 patients with hepatitis B virus (HBV)-HCC], it was demonstrated that cadherin 17 (CDH17) significantly correlated with CK19 expression (R

Indexed as

cadherin 17cytokeratin 19hepatocellular carcinomahepatomakeratin 19prognosisrecurrence

Identifiers

PMID29387234
PMCPMC5768062
OpenAlexW2765172419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.