Evidence map›Paper›PMID 29387058›Full record

ArticleFrontiers in immunology2017

Adaptive Natural Killer Cells Integrate Interleukin-18 during Target-Cell Encounter.

Quirin Hammer, Timo Rückert, Josefine Dunst, Chiara Romagnani

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

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  7. Expansions of adaptive-like NK cells with a tissue-resident phenotype in human lung and blood.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Quirin HammerInnate Immunity, German Rheumatism Research Center (DRFZ), Leibniz Association, Berlin, Germany.
Timo RückertInnate Immunity, German Rheumatism Research Center (DRFZ), Leibniz Association, Berlin, Germany.
Josefine DunstInflammation Biology, German Rheumatism Research Center (DRFZ), Leibniz Association, Berlin, Germany.
Chiara RomagnaniInnate Immunity, German Rheumatism Research Center (DRFZ), Leibniz Association, Berlin, Germany.
German Rheumatism Research Centre · DELeibniz Association · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) infection induces adaptations in the natural killer (NK)-cell compartment. Expanded subsets of adaptive NK cells display potent effector functions against cellular targets, despite their apparent unresponsiveness to stimulation with classical dendritic cell-derived cytokines interleukin (IL)-12 and IL-18. However, it remains unclear whether adaptive NK cells have completely lost their ability to sense inflammation

Indexed as

adaptive natural killer cellscostimulationhuman natural killer cellsinterleukin-18NKG2C

Identifiers

PMID29387058
PMCPMC5776097
OpenAlexW2783148002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.