Evidence map›Paper›PMID 29387005›Full record

ArticleFrontiers in aging neuroscience2017

[

Matthias Brendel, Sonja Schönecker, Günter Höglinger, Simon Lindner, Joachim Havla, Janusch Blautzik, Julia Sauerbeck, Guido Rohrer, Christian Zach, Franziska Vettermann and 11 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Tau accumulation is associated with dopamine deficiency in vivo in four-repeat tauopathies.European journal of nuclear medicine and molecular imaging · 2024
    Article
  8. Clinical application of MAO-B PET usingGeriatrics & gerontology international · 2024
    Review
  9. Review
  10. Review
  11. Pathomechanisms of cognitive impairment in progressive supranuclear palsy.Journal of neural transmission (Vienna, Austria : 1996) · 2023
    Review
  12. Article
  13. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Observational
  14. International consensus on the use of tau PET imaging agentEuropean journal of nuclear medicine and molecular imaging · 2022
    Article
  15. Article
  16. Frontiers in aging neuroscience · 2022
    Article
  17. Imaging pathological tau in atypical parkinsonisms: A review.Clinical parkinsonism & related disorders · 2022
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 7 institutions in 4 countries.

Matthias BrendelDepartment of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Sonja SchöneckerDepartment of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.
Günter HöglingerGerman Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Simon LindnerDepartment of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Joachim HavlaDepartment of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.
Janusch BlautzikDepartment of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Julia SauerbeckDepartment of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Guido RohrerDepartment of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.
Christian ZachDepartment of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Franziska VettermannDepartment of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Anthony E LangMorton and Gloria Shulman Movement Disorders Clinic and the Edmond J. Safra Program in Parkinson's Disease, and Toronto Western Hospital, University of Toronto, Toronto, ON, Canada.
Lawrence GolbeDepartment of Neurology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States.
Georg NüblingDepartment of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.
Peter BartensteinDepartment of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Katsutoshi FurukawaDivision of Community Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Aiko IshikiDepartment of Geriatrics and Gerontology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Kai BötzelDepartment of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.
Adrian DanekDepartment of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.
Nobuyuki OkamuraDivision of Pharmacology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Johannes LevinDepartment of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.
Axel RomingerDepartment of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Ludwig-Maximilians-Universität München · DETohoku Medical and Pharmaceutical University · JPGerman Center for Neurodegenerative Diseases · DERutgers, The State University of New Jersey · USTechnical University of Munich · DETohoku University · JPToronto Western Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive supranuclear palsy (PSP) is a neurodegenerative movement disorder characterized by deposition of fibrillar aggregates of 4R tau-protein in neurons and glial cells of the brain. These deposits are a key neuropathological finding, allowing a diagnosis of "definite PSP," which is usually established post mortem. To date criteria for clinical diagnosis of PSP

Indexed as

[18F]-THK5351disease severityPETprogressive supranuclear palsyPSPRS

Identifiers

PMID29387005
PMCPMC5776329
OpenAlexW2794224336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.