ArticleCancer management and research2018
Young age increases risk for lymph node positivity but decreases risk for non-small cell lung cancer death.
Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Tumor volume may be a better indicator than diameter for occult lymph node metastasis in patients with clinical stage-1 lung cancer.Updates in surgery · 2026Article
- Sonographic Assessment of Peripheral Lymph Nodes In Early-Stage Mycosis Fungoides: Diagnostic Value And Prognostic Implications.Dermatology practical & conceptual · 2026Article
- Machine learning-based prediction of N2 lymph node metastasis in non-small cell lung cancer.BMC pulmonary medicine · 2025Article
- Article
- A Nomogram for Predicting Cancer-Specific Survival in Young Patients With Advanced Lung Cancer Based on Competing Risk Model.The clinical respiratory journal · 2024Article
- The role of adenocarcinoma subtypes and immunohistochemistry in predicting lymph node metastasis in early invasive lung adenocarcinoma.BMC cancer · 2024Article
- A machine learning tool to improve prediction of mediastinal lymph node metastases in non-small cell lung cancer using routinely obtainable [European journal of nuclear medicine and molecular imaging · 2023Article
- Age does matter in adolescents and young adults vs. older adults with lung adenocarcinoma: A retrospective analysis comparing clinical characteristics and outcomes in response to systematic treatments.Oncology letters · 2022Article
- Wide Next-Generation Sequencing Characterization of Young Adults Non-Small-Cell Lung Cancer Patients.Cancers · 2022Article
- Epidemiology and prognosis in young lung cancer patients aged under 45 years old in northern China.Scientific reports · 2021Article
- Young age increases the risk of lymph-node metastasis in patients with muscle-invasive bladder urothelial carcinoma.BMC cancer · 2020Article
- Development of a nomogram for preoperative prediction of lymph node metastasis in non-small cell lung cancer: a SEER-based study.Journal of thoracic disease · 2020Article
- Age-different extent of resection for clinical IA non-small cell lung cancer: analysis of nodal metastasis.Scientific reports · 2020Article
- [Current Situation of Clinical Feature and Gene Phenotype of Young Adult Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2020Review
- Development and validation of nomograms for predicting overall and cancer-specific survival in young patients with non-small cell lung cancer.Journal of thoracic disease · 2020Article
- Lymph node metastasis in young and middle-aged papillary thyroid carcinoma patients: a SEER-based cohort study.BMC cancer · 2020Article
- RNSCLC-PRSP software to predict the prognostic risk and survival in patients with resected TBioData mining · 2019Article
- Effect of Age on Prognosis of Gastric Signet-Ring Cell Carcinoma: A SEER Database Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
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10 authors.
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Abstract
Non-small cell lung cancer (NSCLC) prognosis and risk of lymph node positivity (LN+) are reference points for reasonable treatments. The aim of the current study was to investigate the effect of age on LN+ and NSCLC death. Data from the Surveillance, Epidemiology, and End Results (SEER) registry were used to identify 82,253 patients with NSCLC diagnosed between 1988 and 2008. All the patients underwent standard lung cancer surgery with lymph node examination. Demographic and clinicopathological parameters were extracted and compared among each age group. Impact of age on LN+ and NSCLC death was evaluated by the Cochran-Armitage trend test and logistic univariate and multivariate analyses for all T stages. Overall, 22,711 (27.60%) patients of the entirety had lymph node metastasis and 28,968 (35.22%) patients died of NSCLC within 5 years. With the increase in age, LN+ rates decreased regardless of T stages (
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