ReviewMolecular vision2017
Insight into the molecular genetics of myopia.
Review in Molecular vision, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Myopia management algorithm. Annexe to the article titled Update and guidance on management of myopia. European Society of Ophthalmology in cooperation with International Myopia Institute.European journal of ophthalmology · 2024Guideline
- A novel NYX gene mutation identified in a Chinese Northeast Han family with high myopia and night blindness.BMC ophthalmology · 2026Article
- AI-guided personalized predictions on myopia progression and interventions.NPJ digital medicine · 2026Article
- The prevalence and demographic profile of myopia among school children in Beirut City, Lebanon.BMC public health · 2025Article
- Connecting the dots: the role of genetics in posterior vitreous detachment.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Review
- Genetics and Clinical Findings Associated with Early-Onset Myopia and Retinal Detachment in Saudi Arabia.Genes · 2025Review
- State of the Art on Inherited Retinal Dystrophies: Management and Molecular Genetics.Journal of clinical medicine · 2025Review
- A novel variant in the keratin 12 gene in a four-generation Chinese family with high myopia.Eye (London, England) · 2024Article
- Myopia in Children: Epidemiology, Genetics, and Emerging Therapies for Treatment and Prevention.Children (Basel, Switzerland) · 2024Review
- Knowledge, attitude, and practice of non-ophthalmic medical staff toward myopia-related fundus lesions.Scientific reports · 2024Article
- Prevalence of myopic eyes in private practice and public care services in Brazil: 11 years of retrospective analysis.Arquivos brasileiros de oftalmologia · 2024Article
- Peripheral Eye Length Evaluation in Myopic Children Undergoing Orthokeratology Treatment for 12 Months Using MRI.Clinical optometry · 2024Article
- Exploring the Research Landscape of High Myopia: Trends, Contributors, and Key Areas of Focus.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Genetic and clinical landscape ofThe British journal of ophthalmology · 2023Article
- High Myopia and Thickness of Extraocular and Masticatory Muscles-7T MRI, Preliminary Study.Journal of clinical medicine · 2023Article
- Myopia control in Mendelian forms of myopia.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2023Article
- The Genetic Confirmation and Clinical Characterization of LOXL3-Associated MYP28: A Common Type of Recessive Extreme High Myopia.Investigative ophthalmology & visual science · 2023Article
- Identification of a Novel Frameshift Variant ofJournal of clinical medicine · 2023Article
- Whole exome sequence analysis in 51 624 participants identifies novel genes and variants associated with refractive error and myopia.Human molecular genetics · 2022Article
- Applications of Artificial Intelligence in Myopia: Current and Future Directions.Frontiers in medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myopia is the most common cause of visual impairment worldwide. Genetic and environmental factors contribute to the development of myopia. Studies on the molecular genetics of myopia are well established and have implicated the important role of genetic factors. With linkage analysis, association studies, sequencing analysis, and experimental myopia studies, many of the loci and genes associated with myopia have been identified. Thus far, there has been no systemic review of the loci and genes related to non-syndromic and syndromic myopia based on the different approaches. Such a systemic review of the molecular genetics of myopia will provide clues to identify additional plausible genes for myopia and help us to understand the molecular mechanisms underlying myopia. This paper reviews recent genetic studies on myopia, summarizes all possible reported genes and loci related to myopia, and suggests implications for future studies on the molecular genetics of myopia.
Indexed as
Identifiers
29386878PMC5757860W2777626229What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.