Evidence map›Paper›PMID 29386651›Full record

ArticleScientific reports2018

Axial elongation measured by long scan depth optical coherence tomography during pilocarpine-induced accommodation in intraocular lens-implanted eyes.

Yilei Shao, Qiuruo Jiang, Di Hu, Lingmin Zhang, Meixiao Shen, Shenghai Huang, Lin Leng, Yimin Yuan, Qi Chen, Dexi Zhu and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yilei ShaoSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Qiuruo JiangSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Di HuSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Lingmin ZhangSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Meixiao ShenSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Shenghai HuangSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Lin LengSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yimin YuanSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Qi ChenSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Dexi ZhuSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jianhua WangBascom Palmer Eye Institute, Department of Ophthalmology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Fan LuSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China. lufan62@mail.eye.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We used an ultra-long scan depth optical coherence tomography (UL-OCT) system to investigate changes in axial biometry of pseudophakic eyes during pilocarpine- induced accommodation. The right eyes from 25 healthy subjects (age range 49 to 84 years) with an intraocular lens (IOL) were imaged twice in the non-accommodative and the accommodative states. A custom-built UL-OCT instrument imaged the whole eye. Then accommodation was induced by two drops of 0.5% pilocarpine hydrochloride separated by a 5-minute interval. Following the same protocol, images were acquired again 30 minutes after the first drop. The central corneal thickness (CCT), anterior chamber depth (ACD), IOL thickness (IOLT), and vitreous length (VL) were obtained using custom automated software. The axial length (AL) was calculated by summing the CCT, ACD, IOLT, and VL. With accommodation, ACD increased by +0.08 ± 0.09 mm, while the VL decreased by -0.04 ± 0.09 mm (paired t-test each, P<0.05). CCT and IOLT remained constant during accommodation (P > 0.05). The non-accommodative AL was 23.47 ± 0.93 mm, and it increased by +0.04 ± 0.04 mm after accommodation (P<0.01). The AL increased and the IOL moved backward during pilocarpine-induced accommodation in pseudophakic eyes.

Indexed as

Lenses, IntraocularAccommodation, OcularAdultAgedAged, 80 and overAxial Length, EyeBiometryCorneaEyeFemaleHumansMaleMiddle AgedPilocarpineReproducibility of ResultsTomography, Optical CoherencePilocarpine

Identifiers

PMID29386651
PMCPMC5792446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.