Evidence map›Paper›PMID 29386538›Full record

ArticleScientific reports2018

A comparative Study of Aptasensor Vs Immunosensor for Label-Free PSA Cancer Detection on GQDs-AuNRs Modified Screen-Printed Electrodes.

Monika Srivastava, Narsingh R Nirala, S K Srivastava, Rajiv Prakash

Open access · goldAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 97 citations in OpenAlex.

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  15. Aptasensors versus immunosensors-Which will prevail?Engineering in life sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Monika SrivastavaSchool of Materials Science and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi, 221005, India.
Narsingh R NiralaSchool of Materials Science and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi, 221005, India.
S K SrivastavaSchool of Materials Science and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi, 221005, India.
Rajiv PrakashSchool of Materials Science and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi, 221005, India. rprakash.mst@iitbhu.ac.in.
Banaras Hindu University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Label-free and sensitive detection of PSA (Prostate Specific Antigen) is still a big challenge in the arena of prostate cancer diagnosis in males. We present a comparative study for label-free PSA aptasensor and PSA immunosensor for the PSA-specific monoclonal antibody, based on graphene quantum dots-gold nanorods (GQDs-AuNRs) modified screen-printed electrodes. GQDs-AuNRs composite has been synthesized and used as an electro-active material, which shows fast electron transfer and catalytic property. Aptamer or anti-PSA has immobilized onto the surface of modified screen printed electrodes. Three techniques are used simultaneously, viz. cyclic voltammetry (CV), differential pulse voltammetry (DPV) and electrochemical impedence spectroscopy (EIS) to investigate the analytical performance of both PSA aptasensor and PSA immunosensor with its corresponding PSA antigen. Under optimum conditions, both sensors show comparable results with an almost same limit of detection (LOD) of 0.14 ng mL

Indexed as

Biosensing TechniquesAptamers, NucleotideCalibrationDielectric SpectroscopyElectrochemical TechniquesElectrodesGoldGraphiteHumansMaleNanotubesPrintingProstate-Specific AntigenProstatic NeoplasmsQuantum DotsReproducibility of ResultsAptamers, NucleotideGoldGraphiteProstate-Specific Antigen

Identifiers

PMID29386538
PMCPMC5792442
OpenAlexW2806973457

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.