SynthesisScientific reports2018
Transcriptomic responses to biotic stresses in Malus x domestica: a meta-analysis study.
Synthesis in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Integrative systems biology analysis of barley transcriptome ─ hormonal signaling against biotic stress.PloS one · 2023Pooled it
- The Regulatory Army of Plant Defense: Transcription Factors in the War for Plant Immunity.International journal of molecular sciences · 2026Review
- Ethylene as the Molecular Coordinator of the Plant Growth-Defense Trade-Off Under Biotic and Abiotic Stresses.International journal of molecular sciences · 2026Review
- Unveiling essential host genes and keystone microorganisms of the olive tree holobiont linked to Verticillium wilt tolerance.Microbiome · 2025Article
- Comprehensive transcriptomic meta-analysis unveils new responsive genes to methyl jasmonate and ethylene inHeliyon · 2024Article
- Meta-analysis ofFrontiers in plant science · 2023Article
- Transcriptome Meta-Analysis Identifies Candidate Hub Genes and Pathways of Pathogen Stress Responses inBiology · 2022Article
- Identification of Candidate Genes Associated With Tolerance to Apple Replant Disease by Genome-Wide Transcriptome Analysis.Frontiers in microbiology · 2022Article
- Transcriptomics of Improved Fruit Retention by Hexanal in 'Honeycrisp' Reveals Hormonal Crosstalk and Reduced Cell Wall Degradation in the Fruit Abscission Zone.International journal of molecular sciences · 2021Article
- EORNA, a barley gene and transcript abundance database.Scientific data · 2021Article
- Application of a portable instrument for rapid and reliable detection of SARS-CoV-2 infection in any environment.Immunological reviews · 2020Article
- Metatranscriptomic Analysis of Multiple Environmental Stresses Identifies RAP2.4 Gene Associated with Arabidopsis Immunity to Botrytis cinerea.Scientific reports · 2019Article
- Article
- Transcriptome analysis provides insights into the stress response crosstalk in apple (Malus × domestica) subjected to drought, cold and high salinity.Scientific reports · 2019Article
- Mapping Gene Markers for Apple Fruit Ring Rot Disease Resistance Using a Multi-omics Approach.G3 (Bethesda, Md.) · 2019Article
- Interaction of roses with a biotrophic and a hemibiotrophic leaf pathogen leads to differences in defense transcriptome activation.Plant molecular biology · 2019Article
- Differential gene regulatory pathways and co-expression networks associated with fire blight infection in apple (Horticulture research · 2019Article
- Identifying Host Molecular Features Strongly Linked With Responses to Huanglongbing Disease in Citrus Leaves.Frontiers in plant science · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
RNA-Seq analysis is a strong tool to gain insight into the molecular responses to biotic stresses in plants. The objective of this work is to identify specific and common molecular responses between different transcriptomic data related to fungi, virus and bacteria attacks in Malus x domestica. We analyzed seven transcriptomic datasets in Malus x domestica divided in responses to fungal pathogens, virus (Apple Stem Grooving Virus) and bacteria (Erwinia amylovora). Data were dissected using an integrated approach of pathway- and gene- set enrichment analysis, Mapman visualization tool, gene ontology analysis and inferred protein-protein interaction network. Our meta-analysis revealed that the bacterial infection enhanced specifically genes involved in sugar alcohol metabolism. Brassinosteroids were upregulated by fungal pathogens while ethylene was highly affected by Erwinia amylovora. Gibberellins and jasmonates were strongly repressed by fungal and viral infections. The protein-protein interaction network highlighted the role of WRKYs in responses to the studied pathogens. In summary, our meta-analysis provides a better understanding of the Malus X domestica transcriptome responses to different biotic stress conditions; we anticipate that these insights will assist in the development of genetic resistance and acute therapeutic strategies. This work would be an example for next meta-analysis works aiming at identifying specific common molecular features linked with biotic stress responses in other specialty crops.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.