ArticleScientific reports2018
Human migration and the spread of malaria parasites to the New World.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
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Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The threat of increased transmission of non-Parasitology · 2023Pooled it
- Spatio-temporal dynamics of Plasmodium falciparum transmission within a spatial unit on the Colombian Pacific Coast.Scientific reports · 2020Trial
- Global-scale population genetic analysis of Plasmodium falciparum identifies region-specific patterns of malaria parasite adaptation.Nature communications · 2026Article
- Asymptomatic and submicroscopic Plasmodium vivax infection: a study previous to malaria-free certification in Argentina.Malaria journal · 2026Article
- Diagnosing P. simium zoonotic malaria infection in the Rio de Janeiro Atlantic forest, Brazil.Scientific reports · 2025Article
- Genome-Wide Selection Scans in Mexican Indigenous Populations Reveal Recent Signatures of Pathogen and Diet Adaptation.Genome biology and evolution · 2025Article
- Contribution of Travelers toJMIR public health and surveillance · 2025Article
- Intra-individual variability in ancient plasmodium DNA recovery highlights need for enhanced sampling.Scientific reports · 2025Article
- Genomic exploration of the journey of Plasmodium vivax in Latin America.PLoS pathogens · 2025Article
- Genetic diversity and haplotype structure of theFrontiers in cellular and infection microbiology · 2025Article
- Genomic analysis of global Plasmodium vivax populations reveals insights into the evolution of drug resistance.Nature communications · 2024Article
- Remarkable Evolutionary Rate Variations Among Lineages and Among Genome Compartments in Malaria Parasites of Mammals.Molecular biology and evolution · 2024Article
- Autochthonous simian malaria in Brazil outside the Amazon: Emergence, zoonotic transmission and implications for disease control.One health (Amsterdam, Netherlands) · 2024Review
- Overview ofComparative medicine · 2024Review
- Molecular detection of sub-microscopic infections and Plasmodium falciparum histidine-rich protein-2 and 3 gene deletions in pre-elimination settings of South Africa.Scientific reports · 2024Article
- Article
- A new long-read mitochondrial-genome protocol (PacBio HiFi) for haemosporidian parasites: a tool for population and biodiversity studies.Malaria journal · 2024Article
- A History of Malaria and Conflict.Parasitology research · 2024Review
- Population genomic evidence of structured and connectedEcology and evolution · 2024Article
- Zoonotic Malaria Risk in Serra Do Mar, Atlantic Forest, Brazil.Microorganisms · 2023Article
4 more citing papers are in PubMed but not listed here.
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Authors and funding
25 authors.
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Abstract
We examined the mitogenomes of a large global collection of human malaria parasites to explore how and when Plasmodium falciparum and P. vivax entered the Americas. We found evidence of a significant contribution of African and South Asian lineages to present-day New World malaria parasites with additional P. vivax lineages appearing to originate from Melanesia that were putatively carried by the Australasian peoples who contributed genes to Native Americans. Importantly, mitochondrial lineages of the P. vivax-like species P. simium are shared by platyrrhine monkeys and humans in the Atlantic Forest ecosystem, but not across the Amazon, which most likely resulted from one or a few recent human-to-monkey transfers. While enslaved Africans were likely the main carriers of P. falciparum mitochondrial lineages into the Americas after the conquest, additional parasites carried by Australasian peoples in pre-Columbian times may have contributed to the extensive diversity of extant local populations of P. vivax.
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