Evidence map›Paper›PMID 29386457›Full record

ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2018

Giant Cell Tumors of the Bone: Changes in Image Features after Denosumab Administration.

Sota Oguro, Shigeo Okuda, Hiroaki Sugiura, Shunsuke Matsumoto, Aya Sasaki, Michiro Susa, Hideo Morioka, Masahiro Jinzaki

Open access · diamondAbstract read
In one paragraph

Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. The efficacy and safety of short-course neoadjuvant denosumab for en bloc spondylectomy in spinal giant cell tumor of bone: a preliminary report.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sota OguroRadiology Department, School of Medicine, Keio University.
Shigeo OkudaRadiology Department, School of Medicine, Keio University.
Hiroaki SugiuraRadiology Department, School of Medicine, Keio University.
Shunsuke MatsumotoRadiology Department, School of Medicine, Keio University.
Aya SasakiPathology Department, School of Medicine, Keio University.
Michiro SusaDepartment of Orthopaedic Surgery, National Defense Medical College Hospital.
Hideo MoriokaDepartment of Orthopaedic Surgery, School of Medicine, Keio University.
Masahiro JinzakiRadiology Department, School of Medicine, Keio University.
Keio University · JPNational Defense Medical College Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the clinical importance in the feature change in giant cell tumors of the bone (GCTB) after denosumab treatment, detected by MRI.

methodsIn 12 patients, MRI and CT of GCTB obtained before and after the treatment retrospectively compared. The tumor size, the signal intensity (SI) ratio between the solid part of the GCTB and muscle, cystic part size, gadolinium enhancement and apparent diffusion coefficient (ADC) value were measured on MRI. The bone formation in the tumor was observed on CT and X-ray.

resultsThe mean number of denosumab injections was 19 ± 10. The follow-up period was up to 2 years. One case showed partial remission, while the other 11 cases were stable. A mean SI ratio on T

conclusionThe decrease of SI ratio on T

Indexed as

Antineoplastic AgentsDenosumabGiant Cell Tumor of BoneHumansMagnetic Resonance ImagingRetrospective StudiesTomography, X-Ray ComputedAntineoplastic AgentsDenosumabdenosumabgiant cell tumor of bonemagnetic resonance imaging

Identifiers

PMID29386457
PMCPMC6196302
OpenAlexW2789377758

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.