Evidence map›Paper›PMID 29386406›Full record

ArticleOpen biology2018

Identification and functional characterization of arginine vasopressin receptor 1A : atypical chemokine receptor 3 heteromers in vascular smooth muscle.

Lauren J Albee, Heather M LaPorte, Xianlong Gao, Jonathan M Eby, You-Hong Cheng, Amanda M Nevins, Brian F Volkman, Vadim Gaponenko, Matthias Majetschak

Open access · goldAbstract read
In one paragraph

Article in Open biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Activation of Chemokine (C-C Motif) Receptor 1 Modulates αJournal of the American Heart Association · 2025
    Article
  3. Article
  4. Article
  5. αPharmacological research · 2023
    Article
  6. Heteromerization between αFEBS letters · 2022
    Article
  7. αProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Article
  9. Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Article
  11. Chemokine receptor antagonists with αJournal of basic and clinical physiology and pharmacology · 2021
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lauren J AlbeeBurn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Stritch School of Medicine, 2160 S. 1st Avenue, Maywood, IL 60153, USA.
Heather M LaPorteBurn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Stritch School of Medicine, 2160 S. 1st Avenue, Maywood, IL 60153, USA.
Xianlong GaoBurn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Stritch School of Medicine, 2160 S. 1st Avenue, Maywood, IL 60153, USA.
Jonathan M EbyBurn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Stritch School of Medicine, 2160 S. 1st Avenue, Maywood, IL 60153, USA.
You-Hong ChengBurn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Stritch School of Medicine, 2160 S. 1st Avenue, Maywood, IL 60153, USA.
Amanda M NevinsDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Brian F VolkmanDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Vadim GaponenkoDepartment of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL 60607, USA.
Matthias MajetschakBurn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Stritch School of Medicine, 2160 S. 1st Avenue, Maywood, IL 60153, USA mmajetschak@luc.edu.ORCID 0000-0002-4086-0887
Loyola University Chicago · USMedical College of Wisconsin · USUniversity of Illinois Chicago · US

Funding

Structural Basis for Chemokine FunctionR01AI058072 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI VOLKMAN, BRIAN F · 2004 to 2019
$4.1M
Structural Basis for Chemokine FunctionR37AI058072 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI Brian F Volkman · 2020 to 2026
$2.8M
Regulation of tyrosine kinase signaling through interaction with membrane lipidsR01CA188427 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GAPONENKO, VADIM V, TYNER, ANGELA L · 2015 to 2019
$2.1M
Chemokine control of cardiovascular function during hemorrhagic shockR01GM107495 · NIGMS · UNIVERSITY OF SOUTH FLORIDA · PI MAJETSCHAK, MATTHIAS · 2014 to 2017
$1.1M
NCI NIH HHS R01 CA188427NIAID NIH HHS R01 AI058072NIAID NIH HHS R37 AI058072NIGMS NIH HHS R01 GM107495
6 · The paper itself

Abstract

Recent observations suggest that atypical chemokine receptor (ACKR)3 and chemokine (C-X-C motif) receptor (CXCR)4 regulate human vascular smooth muscle function through hetero-oligomerization with α

Indexed as

Protein MultimerizationAnimalsArginine Vasopressinbeta-ArrestinsCells, CulturedHEK293 CellsHumansInositol PhosphatesMaleMuscle, Smooth, VascularRatsRats, Sprague-DawleyReceptors, CXCRReceptors, VasopressinACKR3 protein, humanArginine VasopressinAVPR1A protein, humanbeta-ArrestinsInositol PhosphatesReceptors, CXCRReceptors, Vasopressinarginine vasopressinCXCL11CXCL12ubiquitinvasoconstrictionvasopressor

Identifiers

PMID29386406
PMCPMC5795052
OpenAlexW2787855413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.