Evidence map›Paper›PMID 29386389›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Mechanism of inhibition of retromer transport by the bacterial effector RidL.

Jialin Yao, Fan Yang, Xiaodong Sun, Shen Wang, Ninghai Gan, Qi Liu, Dingdong Liu, Xia Zhang, Dawen Niu, Yuquan Wei and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Identification of a VPS29 isoform with restricted association to Retriever and Retromer accessory proteins through autoinhibition.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Journal of bacteriology · 2024
    Review
  5. Article
  6. FAM91A1-TBC1D23 complex structure reveals human genetic variations susceptible for PCH.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Article
  8. Eat or Be Eaten: Strategies Used byInfection and immunity · 2023
    Review
  9. Receptor Recycling by Retromer.Molecular and cellular biology · 2023
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. ThemBio · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. The retromer is co-opted to deliver lipid enzymes for the biogenesis of lipid-enriched tombusviral replication organelles.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Jialin YaoKey Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Pediatrics, Division of Neurology, West China Second University Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041 Chengdu, China.
Fan YangKey Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Pediatrics, Division of Neurology, West China Second University Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041 Chengdu, China.
Xiaodong SunDepartment of Pharmacology, West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, 610041 Chengdu, China.
Shen WangKey Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and the Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, 430074 Wuhan, China.
Ninghai GanPurdue Institute for Inflammation, Immunology and Infectious Disease and Department of Biological Sciences, Purdue University, West Lafayette, IN 47907.
Qi LiuKey Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Pediatrics, Division of Neurology, West China Second University Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041 Chengdu, China.
Dingdong LiuKey Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Pediatrics, Division of Neurology, West China Second University Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041 Chengdu, China.
Xia ZhangKey Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Pediatrics, Division of Neurology, West China Second University Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041 Chengdu, China.
Dawen NiuKey Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Pediatrics, Division of Neurology, West China Second University Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041 Chengdu, China.
Yuquan WeiKey Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Pediatrics, Division of Neurology, West China Second University Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041 Chengdu, China.
Cong MaKey Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and the Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, 430074 Wuhan, China.
Zhao-Qing LuoPurdue Institute for Inflammation, Immunology and Infectious Disease and Department of Biological Sciences, Purdue University, West Lafayette, IN 47907.
Qingxiang SunDepartment of Pathology, West China Hospital, Sichuan University, 610041 Chengdu, China qingxiang.sun@scu.edu.cn jiada@scu.edu.cn.
Da JiaKey Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Pediatrics, Division of Neurology, West China Second University Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, 610041 Chengdu, China; qingxiang.sun@scu.edu.cn jiada@scu.edu.cn.ORCID 0000-0002-2205-1998
Sichuan University · CNHuazhong University of Science and Technology · CNPurdue University West Lafayette · USWest China Medical Center of Sichuan University · CN

Funding

Effector-mediated Ubiquitin Manipulation in Legionella Pneumophila PathogenesisR01AI127465 · NIAID · PURDUE UNIVERSITY · PI Qing Deng · 2017 to 2026
$3.4M
NIAID NIH HHS R01 AI127465
6 · The paper itself

Abstract

Retrograde vesicle trafficking pathways are responsible for returning membrane-associated components from endosomes to the Golgi apparatus and the endoplasmic reticulum (ER), and they are critical for maintaining organelle identity, lipid homeostasis, and many other cellular functions. The retrograde transport pathway has emerged as an important target for intravacuolar bacterial pathogens. The opportunistic pathogen

Indexed as

Protein MultimerizationBacterial ProteinsCrystallography, X-RayEndosomesGTPase-Activating ProteinsHeLa CellsHumansLegionella pneumophilaLegionnaires' DiseaseProtein ConformationProtein DomainsProtein TransportVesicular Transport ProteinsBacterial ProteinsGTPase-Activating ProteinsTBC1D5 protein, humanVesicular Transport Proteinsendosomal sortinghost–pathogen interactionretromervesicular trafficking

Identifiers

PMID29386389
PMCPMC5816186
OpenAlexW2792995735

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.