Evidence map›Paper›PMID 29386250›Full record

ArticleDiabetes care2018

Differential Association of Microvascular Attributions With Cardiovascular Disease in Patients With Long Duration of Type 1 Diabetes.

Daniel Gordin, Valma Harjutsalo, Liane Tinsley, Ward Fickweiler, Jennifer K Sun, Carol Forsblom, Peter S Amenta, David Pober, Stephanie D'Eon, Maya Khatri and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 3 countries.

Daniel GordinDianne Nunnally Hoppes Laboratory Section of Vascular Cell Biology, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Valma HarjutsaloAbdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0003-3568-9779
Liane TinsleyDianne Nunnally Hoppes Laboratory Section of Vascular Cell Biology, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Ward FickweilerDianne Nunnally Hoppes Laboratory Section of Vascular Cell Biology, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Jennifer K SunDianne Nunnally Hoppes Laboratory Section of Vascular Cell Biology, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Carol ForsblomAbdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Peter S AmentaDianne Nunnally Hoppes Laboratory Section of Vascular Cell Biology, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
David PoberDianne Nunnally Hoppes Laboratory Section of Vascular Cell Biology, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Stephanie D'EonDianne Nunnally Hoppes Laboratory Section of Vascular Cell Biology, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Maya KhatriDianne Nunnally Hoppes Laboratory Section of Vascular Cell Biology, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Isaac E StillmanDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, MA.
Per-Henrik GroopAbdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0003-4055-6954
Hillary A KeenanDianne Nunnally Hoppes Laboratory Section of Vascular Cell Biology, Joslin Diabetes Center, Harvard Medical School, Boston, MA george.king@joslin.harvard.edu hillary.keenan@joslin.harvard.edu.ORCID 0000-0003-4172-5537
George L KingDianne Nunnally Hoppes Laboratory Section of Vascular Cell Biology, Joslin Diabetes Center, Harvard Medical School, Boston, MA george.king@joslin.harvard.edu hillary.keenan@joslin.harvard.edu.ORCID 0000-0002-0335-5881
Joslin Diabetes Center · USUniversity of Helsinki · FIBeth Israel Deaconess Medical Center · US

Funding

HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
TRAINING IN DIABETES AND METABOLISMT32DK007260 · NIDDK · JOSLIN DIABETES CENTER · PI LAURIE J GOODYEAR · 1986 to 2026
$13.6M
Validation of Potential Protective Factors from Diabetic ComplicationsDP3DK094333 · NIDDK · JOSLIN DIABETES CENTER · PI KING, GEORGE L · 2011 to 2015
$4.1M
Pyruvate kinase M2 levels and activation as protective factors for diabetic nephropathyDP3DK112192 · NIDDK · JOSLIN DIABETES CENTER · PI KING, GEORGE L · 2016 to 2016
$2.3M
Biomarkers for protection against complications and beta-cell destruction R24DK083957 · NIDDK · JOSLIN DIABETES CENTER · PI KING, GEORGE L · 2009 to 2009
$330k
NCRR NIH HHS UL1 RR025758NIDDK NIH HHS DP3 DK094333NIDDK NIH HHS DP3 DK112192NIDDK NIH HHS P30 DK036836NIDDK NIH HHS R24 DK083957NIDDK NIH HHS T32 DK007260
6 · The paper itself

Abstract

objectiveIndependent association of chronic kidney disease (CKD) and proliferative diabetic retinopathy (PDR) with cardiovascular disease (CVD) has not been established. In the Joslin 50-Year Medalist study, characterizing individuals with type 1 diabetes for 50 years or more, we examined the associations of CKD and PDR with CVD, which was validated by another cohort with type 1 diabetes from Finland. RESEARCH DESIGN AND

methodsThis cross-sectional study characterized U.S. residents (

resultsCVD prevalence in the Medalists with CKD and without PDR (+CKD/-PDR) (

conclusionsAbsence of PDR in people with type 1 diabetes and CKD was associated with a decreased prevalence of CVD, suggesting that common protective factors for PDR and CVD may exist.

Indexed as

AgedBody Mass IndexCardiovascular DiseasesCholesterolCross-Sectional StudiesDiabetes Mellitus, Type 1Diabetic NephropathiesDiabetic RetinopathyFemaleFinlandGlomerular Filtration RateGlycated HemoglobinHumansLogistic ModelsLongitudinal StudiesMaleCholesterolGlycated HemoglobinTriglycerides

Identifiers

PMID29386250
PMCPMC5860842
OpenAlexW2790513395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.