Evidence map›Paper›PMID 29386181›Full record

ArticleBMJ (Clinical research ed.)2018

Migraine and risk of cardiovascular diseases: Danish population based matched cohort study.

Kasper Adelborg, Szimonetta Komjáthiné Szépligeti, Louise Holland-Bill, Vera Ehrenstein, Erzsébet Horváth-Puhó, Victor W Henderson, Henrik Toft Sørensen

Open access · hybridAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ (Clinical research ed.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 12 pooled it
21.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 12 syntheses or guidelines pooled it, 297 citations in OpenAlex.

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  3. Association between migraine and cognitive impairment.The journal of headache and pain · 2022
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  6. Beta-Blocker Landiolol Hydrochloride in Preventing Atrial Fibrillation Following Cardiothoracic Surgery: A Systematic Review and Meta-Analysis.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2022
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  12. The efficacy and safety of calcitonin gene-related peptide monoclonal antibody for episodic migraine: a meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2018
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77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Kasper AdelborgDepartment of Clinical Epidemiology, Aarhus University Hospital, Denmark kade@clin.au.dk.
Szimonetta Komjáthiné SzépligetiDepartment of Clinical Epidemiology, Aarhus University Hospital, Denmark.
Louise Holland-BillDepartment of Clinical Epidemiology, Aarhus University Hospital, Denmark.
Vera EhrensteinDepartment of Clinical Epidemiology, Aarhus University Hospital, Denmark.
Erzsébet Horváth-PuhóDepartment of Clinical Epidemiology, Aarhus University Hospital, Denmark.
Victor W HendersonDepartment of Clinical Epidemiology, Aarhus University Hospital, Denmark.
Henrik Toft SørensenDepartment of Clinical Epidemiology, Aarhus University Hospital, Denmark.
Aarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the risks of myocardial infarction, stroke (ischaemic and haemorrhagic), peripheral artery disease, venous thromboembolism, atrial fibrillation or atrial flutter, and heart failure in patients with migraine and in a general population comparison cohort.

designNationwide, population based cohort study.

settingAll Danish hospitals and hospital outpatient clinics from 1995 to 2013.

participants51 032 patients with migraine and 510 320 people from the general population matched on age, sex, and calendar year.

main outcome measuresComorbidity adjusted hazard ratios of cardiovascular outcomes based on Cox regression analysis.

resultsHigher absolute risks were observed among patients with incident migraine than in the general population across most outcomes and follow-up periods. After 19 years of follow-up, the cumulative incidences per 1000 people for the migraine cohort compared with the general population were 25

conclusionsMigraine was associated with increased risks of myocardial infarction, ischaemic stroke, haemorrhagic stroke, venous thromboembolism, and atrial fibrillation or atrial flutter. Migraine may be an important risk factor for most cardiovascular diseases.

Indexed as

AdultAtrial FibrillationBody Mass IndexCardiovascular DiseasesCohort StudiesComorbidityDenmarkFemaleHeart FailureHumansIncidenceIntracranial HemorrhagesMaleMiddle AgedMigraine DisordersMyocardial Infarction

Identifiers

PMID29386181
PMCPMC5791041
OpenAlexW2792403667

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.