Evidence map›Paper›PMID 29386066›Full record

ArticleJournal of medical case reports2018

Carcinoid heart disease revealed by cyanosis with both right and left valvular involvement: a case report.

Khadija Khay, Salim Arous, Tarik Bentaoune, Abdenasser Drighil, Rachida Habbal

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Carcinoid Heart Disease.Journal of the advanced practitioner in oncology · 2024
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Khadija KhayDepartment of Cardiology, Ibn Rushd University Hospital, Casablanca, Morocco.
Salim ArousDepartment of Cardiology, Ibn Rushd University Hospital, Casablanca, Morocco. Arous.salim@hotmail.fr.
Tarik BentaouneDepartment of Cardiology, Ibn Rushd University Hospital, Casablanca, Morocco.
Abdenasser DrighilDepartment of Cardiology, Ibn Rushd University Hospital, Casablanca, Morocco.
Rachida HabbalDepartment of Cardiology, Ibn Rushd University Hospital, Casablanca, Morocco.
Centre Hospitalier Universitaire Ibn Rochd · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarcinoid heart disease is a frequent complication of carcinoid syndrome. It is related to the release by the carcinoid tumor and/or its metastases of bioactive substances such as serotonin. It is characterized by right-sided valvular involvement and can lead to right-sided heart failure. It is a prognostic factor of carcinoid syndrome. CASE PRESENTATION: We report the case of a 53-year-old African woman with an endocrine tumor of her small intestine complicated by carcinoid heart disease, revealed by right-sided heart failure. The diagnosis was confirmed by transthoracic echocardiography, which showed a severe tricuspid regurgitation with a patent foramen ovale, and by increased serum chromogranin A and urinary 5-hydroxyindoleacetic acid. Initially she was treated with medical therapy (furosemide and injection of somatostatin). Afterwards she was proposed for surgery. The evolution of her treatment was good.

conclusionsCarcinoid syndrome is complicated in 60% of the cases of a heart disease, and is responsible for an important morbidity and mortality. The prognosis of patients with carcinoid heart disease has improved in recent years through somatostatin analogues and the cardiac surgery.

Indexed as

EchocardiographyCarcinoid Heart DiseaseCardiac Surgical ProceduresComorbidityCyanosisFemaleForamen Ovale, PatentHeart FailureHormonesHumansIntestinal NeoplasmsMiddle AgedSomatostatinTreatment OutcomeHormonesSomatostatinCarcinoid syndromeCarcinoid tumorsCardiac surgeryFibrosis

Identifiers

PMID29386066
PMCPMC5791312
OpenAlexW2800841886

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.