Evidence map›Paper›PMID 29385926›Full record

ArticleNeurosurgical focus2018

Magnetic resonance-guided interstitial high-intensity focused ultrasound for brain tumor ablation.

Jacquelyn MacDonell, Niravkumar Patel, Sebastian Rubino, Goutam Ghoshal, Gregory Fischer, E Clif Burdette, Roy Hwang, Julie G Pilitsis

Abstract readTechnical Report
In one paragraph

Article in Neurosurgical focus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Glioblastoma Therapy: Past, Present and Future.International journal of molecular sciences · 2024
    Review
  7. Review
  8. Review
  9. Surgical Management of Brain Tumors with Focused Ultrasound.Current oncology (Toronto, Ont.) · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. NeuroPlan: A Surgical Planning Toolkit for an MRI-Compatible Stereotactic Neurosurgery Robot.... International Symposium on Medical Robotics. International Symposium on Medical Robotics · 2021
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jacquelyn MacDonellDepartments of 1 Neuroscience and Experimental Therapeutics and.
Niravkumar PatelRobotics Engineering Program, Worcester Polytechnic Institute, Worcester, Massachusetts; and.
Sebastian RubinoDepartments of 1 Neuroscience and Experimental Therapeutics and.
Goutam GhoshalAcoustic MedSystems, Inc., Savoy, Illinois.
Gregory FischerRobotics Engineering Program, Worcester Polytechnic Institute, Worcester, Massachusetts; and.
E Clif BurdetteAcoustic MedSystems, Inc., Savoy, Illinois.
Roy HwangDepartments of 1 Neuroscience and Experimental Therapeutics and.
Julie G PilitsisDepartments of 1 Neuroscience and Experimental Therapeutics and.

Funding

MR-Guided Precision Conformal Ablation Therapy for Brain TumorsR01CA166379 · NCI · WORCESTER POLYTECHNIC INSTITUTE · PI FISCHER, GREGORY S, PILITSIS, JULIE GEORGIA · 2013 to 2022
$6.5M
NCI NIH HHS R01 CA166379
6 · The paper itself

Abstract

Currently, treatment of brain tumors is limited to resection, chemotherapy, and radiotherapy. Thermal ablation has been recently explored. High-intensity focused ultrasound (HIFU) is being explored as an alternative. Specifically, the authors propose delivering HIFU internally to the tumor with an MRI-guided robotic assistant (MRgRA). The advantage of the authors' interstitial device over external MRI-guided HIFU (MRgHIFU) is that it allows for conformal, precise ablation and concurrent tissue sampling. The authors describe their workflow for MRgRA HIFU delivery.

Indexed as

Brain NeoplasmsHumansLaser TherapyMagnetic Resonance ImagingRobotic Surgical ProceduresUltrasonography, Interventionalbrain tumorDOF = degrees of freedomGBM = glioblastomaHIFU = high-intensity focused ultrasoundhigh-intensity focused ultrasoundLITT = laser interstitial thermal therapyMRgHIFU = MRI-guided HIFUMRgRA = MRI-guided robot assistantMRI guidedMRIT = MRI thermometryneural ablationSRS = stereotactic radiosurgery

Identifiers

PMID29385926
PMCPMC5907801

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.