Evidence map›Paper›PMID 29385738›Full record

ArticleMolecules (Basel, Switzerland)2018

Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity.

Carmela Saturnino, Fedora Grande, Stefano Aquaro, Anna Caruso, Domenico Iacopetta, Maria Grazia Bonomo, Pasquale Longo, Dominique Schols, Maria Stefania Sinicropi

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
76.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 483 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Discoveries and developments of CXCR4-targeted HIV-1 entry inhibitors.Experimental biology and medicine (Maywood, N.J.) · 2020
    Review
  6. Carbazole Derivatives as Antiviral Agents: An Overview.Molecules (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Carmela SaturninoDepartment of Science, University of Basilicata, 85100 Potenza, Italy. carmela.saturnino@unibas.it.
Fedora GrandeDepartment of Pharmacy, Health & Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy. fedora.grande@unical.it.ORCID 0000-0002-6154-4330
Stefano AquaroDepartment of Pharmacy, Health & Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy. stefano.aquaro@unical.it.
Anna CarusoDepartment of Pharmacy, Health & Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy. anna.caruso@unical.it.
Domenico IacopettaDepartment of Pharmacy, Health & Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy. domenico.iacopetta@unical.it.ORCID 0000-0001-5179-7118
Maria Grazia BonomoDepartment of Science, University of Basilicata, 85100 Potenza, Italy. mariagrazia.bonomo@unibas.it.
Pasquale LongoDepartment of Chemistry and Biology, University of Salerno, 84084 Fisciano, Italy. plongo@unisa.it.
Dominique ScholsKU Leuven, Rega Institute for Medical Research, Herestraat 49, B-3000 Leuven, Belgium. dominique.schols@kuleuven.be.ORCID 0000-0003-3256-5850
Maria Stefania SinicropiDepartment of Pharmacy, Health & Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy. s.sinicropi@unical.it.ORCID 0000-0003-2435-8931
University of Calabria · ITUniversity of Basilicata · ITRega Institute for Medical Research · BEUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the progress achieved by anti-retroviral drug research in the last decades, the discovery of novel compounds endowed with selective antiviral activity and reduced side effects is still a necessity. At present, the most urgent requirement includes the improvement of HIV (Human Immunodeficiency Virus) prevention and sexual transmission and the development of new drugs to treat the chronic lifelong infection.

methodsSix chloro-1,4-dimethyl-9 RESULTS AND

conclusiona preliminary biological investigation on the synthesized small series of chloro-1,4-dimethyl-9

Indexed as

Anti-HIV AgentsCarbazolesCell LineHIV InfectionsHumansAnti-HIV AgentsCarbazolesantiviral agentscarbazole derivativesHIV

Identifiers

PMID29385738
PMCPMC6017966
OpenAlexW2785546350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.