Evidence map›Paper›PMID 29385698›Full record

ArticleScientia pharmaceutica2018

Theoretical and Experimental Studies on Inclusion Complexes of Pinostrobin and β-Cyclodextrins.

Jintawee Kicuntod, Kanyani Sangpheak, Monika Mueller, Peter Wolschann, Helmut Viernstein, Saeko Yanaka, Koichi Kato, Warinthorn Chavasiri, Piamsook Pongsawasdi, Nawee Kungwan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientia pharmaceutica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Aurisin A Complexed with 2,6-Di-International journal of molecular sciences · 2022
    Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Jintawee KicuntodStructural and Computational Biology Research Group, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. jintawee.ki@gmail.com.
Kanyani SangpheakProgram in Biotechnology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. swaratchada@gmail.com.
Monika MuellerDepartment of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, 1090 Vienna, Austria. monika.mueller@univie.ac.at.
Peter WolschannStructural and Computational Biology Research Group, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. karl.peter.wolschann@univie.ac.at.
Helmut ViernsteinDepartment of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, 1090 Vienna, Austria. helmut.viernstein@univie.ac.at.
Saeko YanakaInstitute for Molecular Science and Okazaki Institute for Integrative Bioscience, National Institutes of Natural Science, 5-1 Higashiyama Myodaiji, Okazaki 444-8787, Japan. saeko-yanaka@ims.ac.jp.
Koichi KatoInstitute for Molecular Science and Okazaki Institute for Integrative Bioscience, National Institutes of Natural Science, 5-1 Higashiyama Myodaiji, Okazaki 444-8787, Japan. kkatonmr@ims.ac.jp.
Warinthorn ChavasiriNatural Products Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. warinthorn.c@chula.ac.th.
Piamsook PongsawasdiStarch and Cyclodextrin Research Unit, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. Piamsook.P@chula.ac.th.
Nawee KungwanDepartment of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand. naweekung@gmail.com.
Thanyada RungrotmongkolStructural and Computational Biology Research Group, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. t.rungrotmongkol@gmail.com.
Chulalongkorn University · THUniversity of Vienna · ATChiang Mai University · THNational Institutes of Natural Sciences · JPOkazaki Institute for Integrative Bioscience · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pinostrobin (PNS) belongs to the flavanone subclass of flavonoids which shows several biological activities such as anti-inflammatory, anti-cancerogenic, anti-viral and anti-oxidative effects. Similar to other flavonoids, PNS has a quite low water solubility. The purpose of this work is to improve the solubility and the biological activities of PNS by forming inclusion complexes with β-cyclodextrin (βCD) and its derivatives, heptakis-(2,6-di-

Indexed as

biological activityinclusion complexationpinostrobinsteered molecular dynamics simulationβ-cyclodextrin

Identifiers

PMID29385698
PMCPMC5874535
OpenAlexW2792675682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.