ArticleJournal of experimental botany2018
The GARP/MYB-related grape transcription factor AQUILO improves cold tolerance and promotes the accumulation of raffinose family oligosaccharides.
Article in Journal of experimental botany, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.
- Network aggregation improves gene function prediction of grapevine gene co-expression networks.Plant molecular biology · 2020Pooled it
- MYB transcription factors in plant cold stress adaptation: integrating phylogeny, signaling networks, and metabolic regulation.Physiology and molecular biology of plants : an international journal of functional plant biology · 2026Review
- Grapevine adaptation to cold and heat stress.Journal of experimental botany · 2025Review
- Integrating Dense Genotyping with High-Throughput Phenotyping Empowers the Genetic Dissection of Berry Quality and Resilience Traits in Grapevine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- CaMYB80 enhances the cold tolerance of pepper by directly targetingHorticulture research · 2024Article
- Article
- Overexpression of VaBAM3 from Vitis amurensis enhances seedling cold tolerance by promoting soluble sugar accumulation and reactive oxygen scavenging.Plant cell reports · 2024Article
- Identification of Key Genes of Fruit Shape Variation in Jujube with Integrating Elliptic Fourier Descriptors and Transcriptome.Plants (Basel, Switzerland) · 2024Article
- Article
- The serine-glycine-one-carbon metabolic network orchestrates changes in nitrogen and sulfur metabolism and shapes plant development.The Plant cell · 2024Article
- Article
- Advances in understanding cold tolerance in grapevine.Plant physiology · 2023Review
- Cloning and Functional Characterization of Cold-Inducible MYB-like 17 Transcription Factor in Rapeseed (International journal of molecular sciences · 2023Article
- Transcription Factor VvDREB2A fromInternational journal of molecular sciences · 2023Article
- The Blinin Accumulation Promoted by CbMYB32 Involved inInternational journal of molecular sciences · 2023Article
- Genome-wide analysis of HSF family and overexpression ofFrontiers in plant science · 2023Article
- Optimizing raffinose family oligosaccharides content in plants: A tightrope walk.Frontiers in plant science · 2023Review
- Discovery of cold-resistance genes in Vitis amurensis using bud-based quantitative trait locus mapping and RNA-seq.BMC genomics · 2022Article
- Overexpression of grape ABA receptor gene VaPYL4 enhances tolerance to multiple abiotic stresses in Arabidopsis.BMC plant biology · 2022Article
- Temperature-phase transcriptomics reveals that hormones and sugars in the phloem of grape participate in tolerance during cold acclimation.Plant cell reports · 2022Article
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Grapevine (Vitis vinifera L.) is a widely cultivated fruit crop whose growth and productivity are greatly affected by low temperatures. On the other hand, wild Vitis species represent valuable genetic resources of natural stress tolerance. We have isolated and characterized a MYB-like gene encoding a putative GARP-type transcription factor from Amur grape (V. amurensis) designated as VaAQUILO. AQUILO (AQ) is induced by cold in both V. amurensis and V. vinifera, and its overexpression results in significantly improved tolerance to cold both in transgenic Arabidopsis and in Amur grape calli. In Arabidopsis, the ectopic expression of VaAQ increased antioxidant enzyme activities and up-regulated reactive oxygen species- (ROS) scavenging-related genes. Comparative mRNA sequencing profiling of 35S:VaAQ Arabidopsis plants suggests that this transcription factor is related to phosphate homeostasis like their Arabidopsis closest homologues: AtHRS1 and AtHHO2. However, when a cold stress is imposed, AQ is tightly associated with the cold-responsive pathway and with the raffinose family oligosaccharides (RFOs), as observed by the up-regulation of galactinol synthase (GoLS) and raffinose synthase genes. Gene co-expression network (GCN) and cis-regulatory element (CRE) analyses in grapevine indicated AQ as potentially regulating VvGoLS genes. Increased RFO content was confirmed in both transgenic Arabidopsis and Amur grape calli overexpressing VaAQ. Taken together, our results imply that AQ improves cold tolerance through promoting the accumulation of osmoprotectants.
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