Evidence map›Paper›PMID 29385094›Full record

ArticleInternational journal of molecular sciences2018

Enhanced Thermostability of Glucose Oxidase through Computer-Aided Molecular Design.

Xiaoyan Ning, Yanli Zhang, Tiantian Yuan, Qingbin Li, Jian Tian, Weishi Guan, Bo Liu, Wei Zhang, Xinxin Xu, Yuhong Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
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  6. Review
  7. DNA Shuffling ofJournal of microbiology and biotechnology · 2022
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  10. Review
  11. Article
  12. Discovery of Novel Angiotensin-Converting Enzyme Inhibitory Peptides fromInternational journal of molecular sciences · 2019
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaoyan NingBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. sjznxy2010@126.com.
Yanli ZhangBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. 18770046997@163.com.
Tiantian YuanBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. nkyswsnn@163.com.
Qingbin LiBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. liqingbin2015@sina.com.
Jian TianBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. tianjian@caas.cn.
Weishi GuanBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. GuanWeiShiwork@163.com.
Bo LiuBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. liubo01@caas.cn.
Wei ZhangBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. zhangwei02@caas.cn.
Xinxin XuBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. xuxinxin@caas.cn.
Yuhong ZhangBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. zhangyuhong@caas.cn.ORCID 0000-0001-5415-1443
Chinese Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucose oxidase (GOD, EC.1.1.3.4) specifically catalyzes the reaction of β-d-glucose to gluconic acid and hydrogen peroxide in the presence of oxygen, which has become widely used in the food industry, gluconic acid production and the feed industry. However, the poor thermostability of the current commercial GOD is a key limiting factor preventing its widespread application. In the present study, amino acids closely related to the thermostability of glucose oxidase from

Indexed as

Computer-Aided DesignHot TemperatureComputational BiologyComputer SimulationEnzyme StabilityFood IndustryFungal ProteinsGlucose OxidasePenicillium chrysogenumFungal ProteinsGlucose Oxidaseglucose oxidasemolecular designsaturation mutagenesisthermostability

Identifiers

PMID29385094
PMCPMC5855647
OpenAlexW2789819725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.