Evidence map›Paper›PMID 29385071›Full record

ArticleMolecules (Basel, Switzerland)2018

Synthesis and In Vitro Antiproliferative Activity of New 1-Phenyl-3-(4-(pyridin-3-yl)phenyl)urea Scaffold-Based Compounds.

Mohammad M Al-Sanea, Mohammed Safwan Ali Khan, Ahmed Z Abdelazem, So Ha Lee, Pooi Ling Mok, Mohammed Gamal, Mohamed E Shaker, Muhammad Afzal, Bahaa G M Youssif, Nesreen Nabil Omar

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The Potential ofMolecules (Basel, Switzerland) · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohammad M Al-SaneaDepartment of Pharmaceutical Chemistry, College of Pharmacy, Aljouf University, Sakaka 2014, Aljouf Province, Saudi Arabia. mmalsanea@ju.edu.sa.
Mohammed Safwan Ali KhanDepartment of Pharmacology, College of Pharmacy, Aljouf University, Sakaka 2014, Aljouf Province, Saudi Arabia. mskhan@ju.edu.sa.ORCID 0000-0002-6186-5740
Ahmed Z AbdelazemDepartment of Biotechnology & Life Sciences, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University, Beni-Suef 62574, Egypt. aznagi2003@gmail.com.
So Ha LeeChemical Kinomics Research Center, Korea Institute of Science and Technology, Seoul 136-791, Korea. lsh6211@kist.re.kr.
Pooi Ling MokDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia. pooi_ling@upm.edu.my.
Mohammed GamalDepartment of Pharmaceutical Chemistry, College of Pharmacy, Aljouf University, Sakaka 2014, Aljouf Province, Saudi Arabia. mgmohamed@ju.edu.sa.ORCID 0000-0002-4674-6516
Mohamed E ShakerDepartment of Pharmacology, College of Pharmacy, Aljouf University, Sakaka 2014, Aljouf Province, Saudi Arabia. mshaker2222@yahoo.com.
Muhammad AfzalDepartment of Pharmacology, College of Pharmacy, Aljouf University, Sakaka 2014, Aljouf Province, Saudi Arabia. afzalgufran@gmail.com.
Bahaa G M YoussifDepartment of Pharmaceutical Chemistry, College of Pharmacy, Aljouf University, Sakaka 2014, Aljouf Province, Saudi Arabia. bgyoussif@ju.edu.sa.ORCID 0000-0002-6834-6548
Nesreen Nabil OmarDepartment of Biochemistry, Faculty of Pharmacy, Modern University for Technology & Information, 11571 Cairo, Egypt. dr.n.nabil@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new series of 1-phenyl-3-(4-(pyridin-3-yl)phenyl)urea derivatives were synthesized and subjected to in vitro antiproliferative screening against National Cancer Institute (NCI)-60 human cancer cell lines of nine different cancer types. Fourteen compounds

Indexed as

Antineoplastic AgentsPhenylurea CompoundsCell Line, TumorCell ProliferationHumansNeoplasmsAntineoplastic AgentsPhenylurea Compoundsactivityantiproliferativecancercell linesynthesisurea derivatives

Identifiers

PMID29385071
PMCPMC6017049

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.