Evidence map›Paper›PMID 29384791›Full record

ArticleEpidemiology (Cambridge, Mass.)2018

Intake of Sugar-sweetened Beverages and Fecundability in a North American Preconception Cohort.

Elizabeth E Hatch, Amelia K Wesselink, Kristen A Hahn, James J Michiel, Ellen M Mikkelsen, Henrik Toft Sorensen, Kenneth J Rothman, Lauren A Wise

Abstract read
In one paragraph

Article in Epidemiology (Cambridge, Mass.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. How Food Choices Impact on Male Fertility.Current nutrition reports · 2023
    Review
  16. Article
  17. Article
  18. The effect of dietary habits on oocyte/sperm quality.Journal of the Turkish German Gynecological Association · 2023
    Article
  19. Review
  20. Development of a nutrition screening tool to identify need for dietetic intervention in female infertility.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elizabeth E Hatch
Amelia K Wesselink
Kristen A Hahn
James J Michiel
Ellen M Mikkelsen
Henrik Toft Sorensen
Kenneth J Rothman
Lauren A Wise

Funding

An internet-based preconception cohort study in North America and DenmarkR01HD086742 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAUREN A WISE · 2016 to 2026
$6.7M
BURPPE:BU Reproductive, Perinatal, and Pediatric Epidemiology Training ProgramT32HD052458 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WERLER, MARTHA M. · 2007 to 2016
$2.0M
Feasibility of an internet-based study of time-to-pregnancy in the United StatesR21HD072326 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WISE, LAUREN A · 2013 to 2014
$337k
Lifestyle and psychosocial determinants of male subfertility: a prospective studyR03HD090315 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WISE, LAUREN A · 2017 to 2018
$165k
NICHD NIH HHS R01 HD086742NICHD NIH HHS R03 HD090315NICHD NIH HHS R21 HD072326NICHD NIH HHS T32 HD052458
6 · The paper itself

Abstract

backgroundDietary factors, including sugar-sweetened beverages, may have adverse effects on fertility. Sugar-sweetened beverages were associated with poor semen quality in cross-sectional studies, and female soda intake has been associated with lower fecundability in some studies.

methodsWe evaluated the association of female and male sugar-sweetened beverage intake with fecundability among 3,828 women planning pregnancy and 1,045 of their male partners in a North American prospective cohort study. We followed participants until pregnancy or for up to 12 menstrual cycles. Eligible women were aged 21-45 (male partners ≥21), attempting conception for ≤6 cycles, and not using fertility treatments. Participants completed a comprehensive baseline questionnaire, including questions on sugar-sweetened beverage consumption during the previous 4 weeks. We estimated time-to-pregnancy from follow-up questionnaires completed every 2 months by the female partner. We calculated adjusted fecundability ratios (FR) and 95% confidence intervals (CIs) according to intake of sugar- sweetened beverages using proportional probabilities regression.

resultsBoth female and male intakes of sugar-sweetened beverages were associated with reduced fecundability (FR = 0.81; 95% CI = 0.70, 0.94 and 0.78; 95% CI = 0.63, 0.95 for ≥7 sugar-sweetened beverages per week compared with none, for females and males, respectively). Fecundability was further reduced among those who drank ≥7 servings per week of sugar-sweetened sodas (FR = 0.75, 95% CI = 0.59, 0.95 for females and 0.67, 95% CI = 0.51, 0.89 for males).

conclusionsSugar-sweetened beverages, particularly sodas and energy drinks, were associated with lower fecundability, but diet soda and fruit juice had little association.

Indexed as

BeveragesAdultCross-Sectional StudiesFemaleFertilityHealth SurveysHumansMaleMiddle AgedNorth AmericaProspective StudiesSweetening AgentsYoung AdultSweetening Agents

Identifiers

PMID29384791
PMCPMC5882510

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.