Evidence map›Paper›PMID 29384790›Full record

ArticleEpidemiology (Cambridge, Mass.)2018

Exposure to Traffic Emissions and Fine Particulate Matter and Computed Tomography Measures of the Lung and Airways.

Mary B Rice, Wenyuan Li, Kirsten S Dorans, Elissa H Wilker, Petter Ljungman, Diane R Gold, Joel Schwartz, Petros Koutrakis, Itai Kloog, Tetsuro Araki and 5 more

Open access · greenAbstract read
In one paragraph

Article in Epidemiology (Cambridge, Mass.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Airway Mucus Plugs in Community-Living Adults: A Study Protocol.medRxiv : the preprint server for health sciences · 2024
    Article
  3. Airway Mucus Plugs in Community-Living Adults: A Study Protocol.Journal of clinical & experimental pathology · 2024
    Article
  4. Article
  5. Ambient air pollution exposure and radiographic pulmonary vascular volumes.Environmental epidemiology (Philadelphia, Pa.) · 2021
    Article
  6. Article
  7. Effect ofSaudi journal of biological sciences · 2020
    Article
  8. Long-term exposure to PMRespiratory research · 2020
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Pollution and Global Health – An Agenda for Prevention.Environmental health perspectives · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Mary B Rice
Wenyuan Li
Kirsten S Dorans
Elissa H Wilker
Petter Ljungman
Diane R Gold
Joel Schwartz
Petros Koutrakis
Itai Kloog
Tetsuro Araki
Hiroto Hatabu
Raul San Jose Estepar
George T O'Connor
Murray A Mittleman
George R Washko
Harvard University · USBrigham and Women's Hospital · USBeth Israel Deaconess Medical Center · USBen-Gurion University of the Negev · ILFramingham Heart Study · USKarolinska Institutet · SE

Funding

Tulane COBRE in Cardiometabolic Diseases Clinical Research CoreP20GM109036 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI Tanika Nicole Kelly · 2016 to 2026
$25.3M
Tulane Clinical Center for Chronic Renal Insufficiency Cohort StudyU01DK060963 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI CHEN, JING, HAMM, L LEE · 2001 to 2025
$13.9M
Training Program in the Epidemiology of CVDT32HL007575 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI BURING, JULIE E., RIDKER, PAUL M. · 1985 to 2019
$5.0M
Air Pollution and the Lung in Health and COPD: Obstructive, Restrictive and Vascular PathwaysK23ES026204 · NIEHS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI RICE, MARY B · 2016 to 2020
$883k
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
NHLBI NIH HHS HHSN268201500001INHLBI NIH HHS N01 HC025195NHLBI NIH HHS T32 HL007575NIDDK NIH HHS U01 DK060963NIEHS NIH HHS K23 ES026204NIGMS NIH HHS P20 GM109036
6 · The paper itself

Abstract

backgroundExposure to ambient air pollution has been associated with lower lung function in adults, but few studies have investigated associations with radiographic lung and airway measures.

methodsWe ascertained lung volume, mass, density, visual emphysema, airway size, and airway wall area by computed tomography (CT) among 2,545 nonsmoking Framingham CT substudy participants. We examined associations of home distance to major road and PM2.5 (2008 average from a spatiotemporal model using satellite data) with these outcomes using linear and logistic regression models adjusted for age, sex, height, weight, census tract median household value and population density, education, pack-years of smoking, household tobacco exposure, cohort, and date. We tested for differential susceptibility by sex, smoking status (former vs. never), and cohort.

resultsThe mean participant age was 60.1 years (standard deviation 11.9 years). Median PM2.5 level was 9.7 µg/m (interquartile range, 1.6). Living <100 m from a major road was associated with a 108 ml (95% CI = 8, 207) higher lung volume compared with ≥400 m away. There was also a log-linear association between proximity to road and higher lung volume. There were no convincing associations of proximity to major road or PM2.5 with the other pulmonary CT measures. In subgroup analyses, road proximity was associated with lower lung density among men and higher odds of emphysema among former smokers.

conclusionsLiving near a major road was associated with higher average lung volume, but otherwise, we found no association between ambient pollution and radiographic measures of emphysema or airway disease.

Indexed as

AdolescentAdultAir PollutionDenmarkEnvironmental ExposureFemaleHumansLung NeoplasmsMaleOdds RatioParticulate MatterRegistriesTomography, X-Ray ComputedVehicle EmissionsYoung AdultParticulate MatterVehicle Emissions

Identifiers

PMID29384790
PMCPMC6095201
OpenAlexW2791426563

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.