Evidence map›Paper›PMID 29384786›Full record

Observational studyCritical care medicine2018

Early Risk and Resiliency Factors Predict Chronic Posttraumatic Stress Disorder in Caregivers of Patients Admitted to a Neuroscience ICU.

Karmel W Choi, Kelly M Shaffer, Emily L Zale, Christopher J Funes, Karestan C Koenen, Tara Tehan, Jonathan Rosand, Ana-Maria Vranceanu

Abstract readObservational Study
In one paragraph

Observational study in Critical care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Can we prevent chronic posttraumatic stress disorder in caregivers of critical care patients?Journal of emergency and critical care medicine (Hong Kong, China) · 2019
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Karmel W ChoiDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA.
Kelly M ShafferDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA.
Emily L ZaleDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA.
Christopher J FunesDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA.
Karestan C KoenenDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA.
Tara TehanPatient Care Service, Massachusetts General Hospital, Boston, MA.
Jonathan RosandDivision of Neurocritical and Emergency Neurology, Department of Neurology, Massachusetts General Hospital, Boston, MA.
Ana-Maria VranceanuDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA.
Massachusetts General Hospital · USHarvard University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Psychosocial Palliative & Community Research in CancerT32CA009461 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI JENNIFER L HAY, Jamie S. Ostroff · 1985 to 2026
$10.1M
Enhancing Scientific Inquiry in Clinical Neurosciences Through Methodology TrainiR25NS088248 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COFFEY, CHRISTOPHER S., GUTMANN, LAURIE · 2014 to 2018
$2.3M
NCI NIH HHS P30 CA008748NCI NIH HHS T32 CA009461NINDS NIH HHS R25 NS088248
6 · The paper itself

Abstract

objectivesInformal caregivers-that is, close family and friends providing unpaid emotional or instrumental care-of patients admitted to ICUs are at risk for posttraumatic stress disorder. As a first step toward developing interventions to prevent posttraumatic stress disorder in ICU caregivers, we examined the predictive validity of psychosocial risk screening during admission for caregiver posttraumatic stress disorder at 3 and 6 months post hospitalization.

designAn observational, prospective study.

participantsNinety-nine caregivers were recruited as part of a longitudinal research program of patient-caregiver dyads in a neuroscience ICU.

interventionNone. MEASUREMENTS AND MAIN

resultsCaregiver posttraumatic stress disorder symptoms were assessed during admission (baseline), 3 months, and 6 months post hospitalization. We 1) characterized prevalence of clinically significant symptoms at each time point 2); calculated sensitivity and specificity of baseline posttraumatic stress disorder screening in predicting posttraumatic stress disorder at 3 and 6 months; and 3) used recursive partitioning to select potential baseline factors and examine the extent to which they helped predict clinically significant posttraumatic stress disorder symptoms at each time point. Rates of caregiver posttraumatic stress disorder remained relatively stable over time (16-22%). Screening for posttraumatic stress disorder at baseline predicted posttraumatic stress disorder at 3 and 6 months with moderate sensitivity (75-80%) and high specificity (92-95%). Screening for posttraumatic stress disorder at baseline was associated with caregiver anxiety, mindfulness (i.e., ability to be aware of one's thoughts and feelings in the moment), and bond with patient. Furthermore, baseline posttraumatic stress disorder screening was the single most relevant predictor of posttraumatic stress disorder at 3 and 6 months, such that other baseline factors did not significantly improve predictive ability.

conclusionsScreening neuroscience ICU caregivers for clinically significant posttraumatic stress disorder symptoms during admission is the single most important way to identify the majority of those likely to suffer from chronic posttraumatic stress disorder following discharge. Addressing early posttraumatic stress disorder symptoms and their psychosocial correlates during admission may help prevent chronic posttraumatic stress disorder in these at-risk caregivers.

Indexed as

Resilience, PsychologicalBrain DiseasesCaregiversFemaleHumansIntensive Care UnitsMaleMiddle AgedProspective StudiesPsychiatric Status Rating ScalesPsychologyRisk FactorsStress Disorders, Post-TraumaticTime Factors

Identifiers

PMID29384786
PMCPMC5899036
OpenAlexW2789544981

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.