Evidence map›Paper›PMID 29384476›Full record

ArticleeLife2018

Activity-induced Ca

Dante J Heredia, Cheng-Yuan Feng, Grant W Hennig, Robert B Renden, Thomas W Gould

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. Optogenetic and Endogenous Modulation of CaInternational journal of molecular sciences · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Peripheral glia diversity.Journal of anatomy · 2022
    Review
  9. Review
  10. Article
  11. Review
  12. Local IPScience advances · 2021
    Article
  13. Cholinesterases in Tripartite Neuromuscular Synapse.Frontiers in molecular neuroscience · 2021
    Review
  14. ADP/P2YMucosal immunology · 2020
    Article
  15. Properties of Glial Cell at the Neuromuscular Junction Are Incompatible with Synaptic Repair in theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  16. Calcium Signaling in Schwann cells.Neuroscience letters · 2020
    Review
  17. Review
  18. Article
  19. Article
  20. Postnatal Restriction of Activity-Induced CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dante J HerediaDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, United States.
Cheng-Yuan FengDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, United States.ORCID http://orcid.org/0000-0002-3278-9451
Grant W HennigDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, United States.
Robert B RendenDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, United States.
Thomas W GouldDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, United States.ORCID http://orcid.org/0000-0003-2154-9388
University of Nevada, Reno · US

Funding

STRETCH DEPENDENT POTASSIUM CHANNEL REGULATION IN OVERACTIVE BLADDERP20RR018751 · NCRR · UNIVERSITY OF NEVADA RENO · PI BAKER, JOSH E · 2003 to 2011
$17.3M
Cell Biology of Signaling across MembranesP20GM103554 · NIGMS · UNIVERSITY OF NEVADA RENO · PI VON BARTHELD, CHRISTOPHER S · 2012 to 2016
$8.0M
Single Cell Molecular ExpressionP30GM110767 · NIGMS · UNIVERSITY OF NEVADA RENO · PI YAN, WEI · 2014 to 2018
$5.4M
Smooth Muscle Plasticity: A COBREP20GM103513 · NIGMS · UNIVERSITY OF NEVADA RENO · PI SANDERS, KENTON M · 2012 to 2013
$4.1M
NCRR NIH HHS 5P20RR018751NCRR NIH HHS P20 RR018751NIGMS NIH HHS GM103554NIGMS NIH HHS GM110767NIGMS NIH HHS P20 GM103513NIGMS NIH HHS P20 GM103554NIGMS NIH HHS P30 GM110767
6 · The paper itself

Abstract

Perisynaptic glial cells respond to neural activity by increasing cytosolic calcium, but the significance of this pathway is unclear. Terminal/perisynaptic Schwann cells (TPSCs) are a perisynaptic glial cell at the neuromuscular junction that respond to nerve-derived substances such as acetylcholine and purines. Here, we provide genetic evidence that activity-induced calcium accumulation in neonatal TPSCs is mediated exclusively by one subtype of metabotropic purinergic receptor. In

Indexed as

Calcium SignalingMuscle FatigueAnimalsMiceMice, TransgenicReceptors, Purinergic P2Y1Schwann CellsReceptors, Purinergic P2Y1calciumfatiguemouseneuromuscularneuroscienceperisynapticpotassiumSchwann

Identifiers

PMID29384476
PMCPMC5798932
OpenAlexW2785751439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.