Evidence map›Paper›PMID 29384416›Full record

ArticleAmerican journal of physiology. Renal physiology2018

Differential roles of WNK4 in regulation of NCC in vivo.

Yih-Sheng Yang, Jian Xie, Sung-Sen Yang, Shih-Hua Lin, Chou-Long Huang

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Transport activity regulates mitochondrial bioenergetics and biogenesis in renal tubules.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. WNKs are potassium-sensitive kinases.American journal of physiology. Cell physiology · 2021
    Article
  11. WNK4 kinase: from structure to physiology.American journal of physiology. Renal physiology · 2021
    Review
  12. Review
  13. Review
  14. Review
  15. WNK4 kinase is a physiological intracellular chloride sensor.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  16. Recent advances in renal epithelial transport.American journal of physiology. Renal physiology · 2019
    Article
  17. WNK-SPAK/OSR1 signaling: lessons learned from an insect renal epithelium.American journal of physiology. Renal physiology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Yih-Sheng YangDivision of Nephrology, Department of Medicine, University of Texas Southwestern Medical Center , Dallas, Texas.
Jian XieDivision of Nephrology, Department of Medicine, University of Texas Southwestern Medical Center , Dallas, Texas.
Sung-Sen YangDivision of Nephrology, Department of Medicine, Tri-Service General Hospital, and Graduate Institute of Medical Sciences, National Defense Medical Center , Taipei , Taiwan.
Shih-Hua LinDivision of Nephrology, Department of Medicine, Tri-Service General Hospital, and Graduate Institute of Medical Sciences, National Defense Medical Center , Taipei , Taiwan.
Chou-Long HuangDivision of Nephrology, Department of Medicine, University of Texas Southwestern Medical Center , Dallas, Texas.
The University of Texas Southwestern Medical Center · USInstitute of Biomedical Sciences, Academia Sinica · TWTri-Service General Hospital · TW

Funding

Membrane Trafficking of Renal Potassium ChannelR01DK059530 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI HUANG, CHOU-LONG · 2003 to 2014
$4.7M
WNK kinase cascade in health and diseaseR01DK111542 · NIDDK · UNIVERSITY OF IOWA · PI Chou-Long Huang · 2017 to 2026
$3.6M
Klotho and Chronic Kidney DiseaseR01DK100605 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI HUANG, CHOU-LONG · 2014 to 2023
$3.5M
Regulation of Renal Calcium Transport in Health and DiseaseR01DK109887 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI HUANG, CHOU-LONG · 2016 to 2020
$1.8M
NIDDK NIH HHS R01 DK059530NIDDK NIH HHS R01 DK100605NIDDK NIH HHS R01 DK109887NIDDK NIH HHS R01 DK111542
6 · The paper itself

Abstract

The Na

Indexed as

AnimalsBiological TransportGene Expression Regulation, EnzymologicInjections, SubcutaneousKidney Tubules, DistalMice, Inbred C57BLMice, KnockoutPhosphorylationPotassium, DietaryProtein Serine-Threonine KinasesRenal EliminationRenal ReabsorptionSodium ChlorideSodium Chloride Symporter InhibitorsSolute Carrier Family 12, Member 3Potassium, DietaryPrkwnk4 protein, mouseProtein Serine-Threonine KinasesSlc12a3 protein, mouseSodium ChlorideSodium Chloride Symporter InhibitorsSolute Carrier Family 12, Member 3DCTdietary potassiumintracellular chlorideNCCWNK1WNK4

Identifiers

PMID29384416
PMCPMC6031911
OpenAlexW2785319551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.