Evidence map›Paper›PMID 29384243›Full record

Trial reportJournal of clinical hypertension (Greenwich, Conn.)2018

Ambulatory blood pressure in the dash diet trial: Effects of race and albuminuria.

Crystal C Tyson, Huiman Barnhart, Shelly Sapp, Victor Poon, Pao-Hwa Lin, Laura P Svetkey

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04084574 (Diet and Hypertension Management in African Americans With Chronic Kidney Disease), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04084574 nacompletednot on this mapstarted 2022, after this paper: background citation

Diet and Hypertension Management in African Americans With Chronic Kidney Disease

TypeinterventionalSponsorDuke UniversityRan2022 to 2023Enrolled31ConditionsChronic Kidney Diseases, High Blood PressureArmsDASH diet counseling
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Ambulatory blood pressure in the dash diet trial: Effects of race and albuminuria.Journal of clinical hypertension (Greenwich, Conn.) · 2018
    Trial
  4. Review
  5. Self-Perceived Barriers and Facilitators to Dietary Approaches to Stop Hypertension Diet Adherence Among Black Americans With Chronic Kidney Disease: A Qualitative Study.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2023
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Crystal C TysonDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.ORCID 0000-0003-2892-3790
Huiman BarnhartDuke Clinical Research Institute, Durham, NC, USA.
Shelly SappDuke Clinical Research Institute, Durham, NC, USA.
Victor PoonDuke Clinical Research Institute, Durham, NC, USA.
Pao-Hwa LinDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Laura P SvetkeyDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.

Funding

Zoledronic Acid in Treatment of Osteoporosis in PostmenoM01RR002635 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI GARBER, JUDY E. · 1985 to 2008
$48.4M
Renal Genomics CoreP30DK096493 · NIDDK · DUKE UNIVERSITY · PI WINN, MICHELLE P. · 2012 to 2016
$5.9M
ZIDOVUDINE WITH PROBENECID--EFFECTS OF PROBENECID ON ZIDOVUDINEM01RR000722 · NCRR · JOHNS HOPKINS UNIVERSITY · 1985 to 1996
–
NCRR NIH HHS M01 RR000722NCRR NIH HHS M01 RR002635NIDDK NIH HHS P30 DK096493
6 · The paper itself

Abstract

We evaluated whether low-grade albuminuria or black race modulates ambulatory blood pressure (BP) or nocturnal BP response to the DASH diet. Among 202 adults enrolled in the DASH multicenter trial who were fed the DASH or control diet for 8 weeks, reductions in 24-hour daytime and nighttime SBP and DBP were significantly larger for DASH compared to control. Median changes in nocturnal BP dipping were not significant. Compared to urine albumin excretion of <7 mg/d, ≥7 mg/d was associated with larger significant median reductions in 24-hour SBP (-7.3 vs -3.1 mm Hg), all measures of DBP (24-hour: -5.9 vs -1.8 mm Hg; daytime: -9.9 vs -4.0 mm Hg; nighttime -9.0 vs -2.0 mm Hg), and with increased nocturnal SBP dipping (2.3% vs -0.5%). Black race was associated with larger median reduction in 24-hour SBP only (-5.5 vs -2.4 mm Hg). This analysis suggests greater effect of DASH on ambulatory BP in the presence of low-grade albuminuria.

Indexed as

AlbuminuriaDietary Approaches To Stop HypertensionHypertensionAdultAntihypertensive AgentsBlack or African AmericanBlood PressureBlood Pressure Monitoring, AmbulatoryFemaleHumansKidney Function TestsMaleMiddle AgedOutcome Assessment, Health CarePatient AcuityUnited StatesAntihypertensive Agentsambulatory blood pressure/home blood pressure monitordiet/nutrition/hypertensionproteinuria

Identifiers

PMID29384243
PMCPMC5820120

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.