Evidence map›Paper›PMID 29383862›Full record

ReviewOral diseases2019

Comparing human and mouse salivary glands: A practice guide for salivary researchers.

C L Maruyama, M M Monroe, J P Hunt, L Buchmann, O J Baker

Abstract readComparative StudyReview
In one paragraph

Review in Oral diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. Laryngoscope investigative otolaryngology · 2023
    Article
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  20. Identifying Fibrogenic Cells Following Salivary Gland Obstructive Injury.bioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

C L MaruyamaUniversity of Utah School of Dentistry, Salt Lake City, UT, USA.
M M MonroeDepartment of Otolaryngology-Head and Neck Surgery, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
J P HuntDepartment of Otolaryngology-Head and Neck Surgery, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
L BuchmannDepartment of Otolaryngology-Head and Neck Surgery, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
O J BakerUniversity of Utah School of Dentistry, Salt Lake City, UT, USA.ORCID http://orcid.org/0000-0002-0628-8645

Funding

THE USE OF FIBRIN HYDROGELS TO PROMOTE SALIVARY GLAND REGENERATIONR01DE022971 · NIDCR · UNIVERSITY OF UTAH · PI ANDREADIS, STELIOS T., BAKER, OLGA JULIANA · 2012 to 2025
$7.2M
A Targeted Approach to Managing Salivary Gland Inflammation Using ResolvinsR01DE027884 · NIDCR · UNIVERSITY OF UTAH · PI BAKER, OLGA JULIANA · 2018 to 2022
$1.7M
RESOLUTION OF CYTOKINE-MEDIATED SALIVARY GLAND INFLAMMATIONR56DE021697 · NIDCR · UNIVERSITY OF UTAH · PI BAKER, OLGA JULIANA · 2017 to 2017
$379k
National Institute of Dental and Craniofacial Research 2R56DE02169707A1 and 5R01DE02297107NIDCR NIH HHS R01 DE022971NIDCR NIH HHS R01 DE027884NIDCR NIH HHS R56 DE021697
6 · The paper itself

Abstract

Mice are a widely utilized in vivo model for translational salivary gland research but must be used with caution. Specifically, mouse salivary glands are similar in many ways to human salivary glands (i.e., in terms of their anatomy, histology, and physiology) and are both readily available and relatively easy and affordable to maintain. However, there are some significant differences between the two organisms, and by extension, the salivary glands derived from them must be taken into account for translational studies. The current review details pertinent similarities and differences between human and mouse salivary glands and offers practical guidelines for using both for research purposes.

Indexed as

Translational Research, BiomedicalAnimalsBioengineeringCytological TechniquesHumansMicePluripotent Stem CellsSalivary Glandsanatomyhistologyphysiologyprimary cellstissue culturetissue engineering

Identifiers

PMID29383862
PMCPMC6613660

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.