Evidence map›Paper›PMID 29383700›Full record

ArticleBritish journal of haematology2019

Venetoclax as a single agent and in combination with PI3K-MTOR1/2 kinase inhibitors against ibrutinib sensitive and resistant mantle cell lymphoma.

Huijuan Jiang, Tint Lwin, Xiaohong Zhao, Yuan Ren, Grace Li, Lynn Moscinski, Bijal Shah, Jianguo Tao

Abstract readLetter
In one paragraph

Article in British journal of haematology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. B-cell non-Hodgkin lymphomas.Lancet (London, England) · 2024
    Review
  4. Article
  5. Article
  6. Programmed cell death, redox imbalance, and cancer therapeutics.Apoptosis : an international journal on programmed cell death · 2021
    Review
  7. Article
  8. Article
  9. Article
  10. Mitochondria in cancer metabolism, an organelle whose time has come?Biochimica et biophysica acta. Reviews on cancer · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huijuan JiangDepartments of Chemical Biology and Molecular Medicine Program, Moffitt Cancer Center, Tampa, FL, USA.
Tint LwinDepartments of Chemical Biology and Molecular Medicine Program, Moffitt Cancer Center, Tampa, FL, USA.
Xiaohong ZhaoDepartments of Chemical Biology and Molecular Medicine Program, Moffitt Cancer Center, Tampa, FL, USA.
Yuan RenDepartments of Chemical Biology and Molecular Medicine Program, Moffitt Cancer Center, Tampa, FL, USA.
Grace LiDepartments of Chemical Biology and Molecular Medicine Program, Moffitt Cancer Center, Tampa, FL, USA.
Lynn MoscinskiDepartments of Chemical Biology and Molecular Medicine Program, Moffitt Cancer Center, Tampa, FL, USA.
Bijal ShahDepartment of Malignant Hematology, Moffitt Cancer Center, Tampa, FL, USA.
Jianguo TaoDepartments of Chemical Biology and Molecular Medicine Program, Moffitt Cancer Center, Tampa, FL, USA.ORCID 0000-0002-7632-1594

Funding

Targeting Negative Regulatory Pathways for Immunotherapy of B-Cell LymphomasR01CA134807 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI TAO, JIANGUO · 2010 to 2014
$2.3M
Role of Specific Histone Deacetylases in Lymphoma Immunobiology and TherapyR01CA179062 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI SOTOMAYOR, EDUARDO M., TAO, JIANGUO · 2015 to 2019
$1.8M
Tageting BAFF and BAFF-Induced Non-Canonical NF-kB Pathways for Enhancing Mantle R01CA137123 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI TAO, JIANGUO · 2009 to 2013
$1.3M
NCI NIH HHS R01 CA134807NCI NIH HHS R01 CA137123NCI NIH HHS R01 CA179062
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenineAntineoplastic Combined Chemotherapy ProtocolsBridged Bicyclo Compounds, HeterocyclicDisease-Free SurvivalFemaleHumansLymphoma, Mantle-CellMalePhosphoinositide-3 Kinase InhibitorsPiperidinesPyrazolesPyrimidinesSulfonamidesSurvival RateTOR Serine-Threonine KinasesAdenineBridged Bicyclo Compounds, HeterocyclicibrutinibMTOR protein, humanPhosphoinositide-3 Kinase InhibitorsPiperidinesPyrazolesPyrimidinesSulfonamidesTOR Serine-Threonine KinasesvenetoclaxBCL2mantle cell lymphomaPI3K/AKT

Identifiers

PMID29383700
PMCPMC6066460

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.