ArticleOphthalmology and therapy2018
Choriocapillaris Vascular Density Changes in Patients with Drusen: Cross-Sectional Study Based on Optical Coherence Tomography Angiography Findings.
Article in Ophthalmology and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Exploring the Maximum Detectable Percentage of Choriocapillaris Flow Deficits Within Geographic Atrophy Using SS-OCT Angiography.Investigative ophthalmology & visual science · 2026Article
- Systemic lipid abnormalities and choriocapillaris flow deficits in patients with hard drusen.Scientific reports · 2026Article
- Impairment of Neurovascular Function in Intermediate Age-Related Macular Degeneration.Translational vision science & technology · 2024Article
- Calcified Drusen Prevent the Detection of Underlying Choriocapillaris Using Swept-Source Optical Coherence Tomography Angiography.Investigative ophthalmology & visual science · 2024Article
- Crosstalk Between Microglia and Müller Glia in the Age-Related Macular Degeneration: Role and Therapeutic Value of Neuroinflammation.Aging and disease · 2024Review
- Spatial Analysis Reveals Vascular Changes in Retinal and Choroidal Vessel Perfusion in Intermediate AMD With Reticular Pseudodrusen.Investigative ophthalmology & visual science · 2024Article
- Vessel density changes in choroid, chorio-capillaries, deep and superficial retinal plexues on OCTA in normal ageing and various stages of age-related macular degeneration.International ophthalmology · 2023Observational
- Early Optical Coherence Tomography Biomarkers for Selected Retinal Diseases-A Review.Diagnostics (Basel, Switzerland) · 2023Review
- Quantitative Imaging Biomarkers in Age-Related Macular Degeneration and Diabetic Eye Disease: A Step Closer to Precision Medicine.Journal of personalized medicine · 2021Review
- Validation of a Compensation Strategy Used to Detect Choriocapillaris Flow Deficits Under Drusen With Swept Source OCT Angiography.American journal of ophthalmology · 2020Observational
- Automated quantification of choriocapillaris anatomical features in ultrahigh-speed optical coherence tomography angiograms.Biomedical optics express · 2019Article
- Vascular Changes in Intermediate Age-Related Macular Degeneration Quantified Using Optical Coherence Tomography Angiography.Translational vision science & technology · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe purpose of this study was to investigate the extent and morphology of the choriocapillaris' density defect in patients with drusen in non-neovascular age-related macular degeneration (AMD).
methodsParticipants in this study were 36 patients with non-neovascular AMD and drusen. All patients underwent best-corrected visual acuity, slit-lamp examination, spectral domain-optical coherence tomography (SD-OCT), and optical coherence tomography angiography (OCTA).
resultsIn all studied cases, the presence of drusen was associated with choriocapillaris' reduced blood flow signal of different extent and severity. Three types of choriocapillaris' non-perfusion were observed, along with an association between the size of drusen and the morphology of choriocapillaris' density defect. Moreover, the extent of choriocapillaris' density change has been related to ellipsoid zone disruption and therefore to visual impairment.
conclusionsOur study showed that in patients with drusen due to non-neovascular AMD, there is choriocapillaris' impairment of different morphology in OCTA, which is mainly related to the size and location of the drusen.
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