Evidence map›Paper›PMID 29383651›Full record

ArticleInfection2018

Rickettsia parkeri infections diagnosed by eschar biopsy, Virginia, USA.

Pamela Kelman, Chelsea Wright Thompson, Wayne Hynes, Christian Bergman, Cameron Lenahan, Joel S Brenner, Michelle G Brenner, Benjamin Goodman, Demetria Borges, Michael Filak and 1 more

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Pamela KelmanVirginia Department of Health, Richmond, VA, USA.
Chelsea Wright ThompsonOld Dominion University, Norfolk, VA, USA.
Wayne HynesOld Dominion University, Norfolk, VA, USA.
Christian BergmanEastern Virginia Medical School, Norfolk, VA, USA.
Cameron LenahanOld Dominion University, Norfolk, VA, USA.
Joel S BrennerEastern Virginia Medical School, Norfolk, VA, USA.
Michelle G BrennerEastern Virginia Medical School, Norfolk, VA, USA.
Benjamin GoodmanEastern Virginia Medical School, Norfolk, VA, USA.
Demetria BorgesFamily Medicine Clifton/Centreville, Centreville, VA, USA.
Michael FilakFamily Medicine Clifton/Centreville, Centreville, VA, USA.
Holly GaffOld Dominion University, Norfolk, VA, USA. hgaff@odu.edu.ORCID http://orcid.org/0000-0002-4034-2684
Eastern Virginia Medical School · USOld Dominion University · USVirginia Department of Health · US

Funding

Spatially-explicit mathematical model of human monocytic ehrlichiosisK25AI067791 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI GAFF, HOLLY · 2007 to 2010
$463k
NIAID NIH HHS K25 AI067791
6 · The paper itself

Abstract

backgroundInfection with Rickettsia parkeri is an emerging tick-borne illness, often accompanied by fever and an eschar at the site of tick attachment. We present three cases of R. parkeri in Virginia residents. CASE PRESENTATIONS: Case 1 presented initially afebrile, failed to seroconvert to rickettsial antigens, and was diagnosed by DNA testing of the eschar. Case 2 presented febrile with eschar, no serologies were performed, and was diagnosed by DNA testing of the eschar. Case 3 presented febrile with eschar, serologies were negative for rickettsial antigens, and was diagnosed by DNA testing of the eschar.

conclusionDNA testing of eschars represents an under-utilized diagnostic test and may aid in cases where the diagnosis is not made clinically.

Indexed as

Antibodies, BacterialBiopsyDoxycyclineHumansMagnetic Resonance ImagingMaleMiddle AgedPolymerase Chain ReactionRickettsiaRickettsia InfectionsSymptom AssessmentTick BitesTomography, X-Ray ComputedVirginiaAntibodies, BacterialDoxycyclineEscharRickettsia parkeriR. parkeri rickettsiosisTidewater spotted fever

Identifiers

PMID29383651
OpenAlexW2791665284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.